open access

Vol 49, No 5 (2015)
Case reports
Submitted: 2015-05-17
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Miller-Fisher syndrome associated with unilateral cerebral white matter lesions

Yongfeng Xu, Lan Liu
DOI: 10.1016/j.pjnns.2015.07.008
·
Neurol Neurochir Pol 2015;49(5):344-347.

open access

Vol 49, No 5 (2015)
Case reports
Submitted: 2015-05-17

Abstract

Miller-Fisher syndrome (MFS) is characterized by classical triad of ophthalmoplegia, ataxia and areflexia. The involvement of cerebral white matter in MFS is very rare. We report a typical MFS patient whose brain MRI showed unilateral and extensive involvement in cerebral white matter. We also found mild pleocytosis and raised protein concentration in cerebrospinal fluid. Deficits resolved completely after treatment with intravenous immunoglobulins. Subsequent brain MRI shows cavity formation in involved white matter.

Abstract

Miller-Fisher syndrome (MFS) is characterized by classical triad of ophthalmoplegia, ataxia and areflexia. The involvement of cerebral white matter in MFS is very rare. We report a typical MFS patient whose brain MRI showed unilateral and extensive involvement in cerebral white matter. We also found mild pleocytosis and raised protein concentration in cerebrospinal fluid. Deficits resolved completely after treatment with intravenous immunoglobulins. Subsequent brain MRI shows cavity formation in involved white matter.

Get Citation

Keywords

Miller-Fisher syndrome, Central nervous system, Pleocytosis

About this article
Title

Miller-Fisher syndrome associated with unilateral cerebral white matter lesions

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 49, No 5 (2015)

Pages

344-347

DOI

10.1016/j.pjnns.2015.07.008

Bibliographic record

Neurol Neurochir Pol 2015;49(5):344-347.

Keywords

Miller-Fisher syndrome
Central nervous system
Pleocytosis

Authors

Yongfeng Xu
Lan Liu

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