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Writing in Richardson variant of progressive supranuclear palsy in comparison to progressive non-fluent aphasia
Affiliations- Neurology Department, St. Adalbert Hospital, Copernicus Podmiot Leczniczy Sp. z o.o., Gdansk, Poland
- Department of Neurological and Psychiatric Nursing, Medical University of Gdansk, Gdańsk, Poland
- Neurology Department, Central Clinical Hospital of the Ministry of Interior, Warsaw, Poland
- Speech Therapy Chair, Faculty of Languages, University of Gdansk, Gdansk, Poland
- Neurological Rehabilitation Department, Specialist Hospital in Koscierzyna, Dzierzazno, Poland
- Neurodegenerative Disorders Department, Mossakowski Medical Research Center, Polish Academy of Sciences, Warsaw, Poland
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Abstract
The overlap between progressive supranuclear palsy (PSP) and progressive non-fluent aphasia (PNFA) is being increasingly recognized. In this paper descriptive writing in patients with Richardson syndrome of progressive supranuclear palsy (PSP-RS) is compared to writing samples from patients with PNFA.
MethodsTwenty-seven patients participated in the study: 17 with the clinical diagnosis of PSP-RS and 10 with PNFA. Untimed written picture description was administered during neuropsychological assessment and subsequently scored by two raters blinded to the clinical diagnosis. Lexical and syntactic content, as well as writing errors (e.g. omission and perseverative errors) were analyzed.
ResultsIn patients with PSP-RS both letter and diacritic mark omission errors were very frequent. Micrographia was present in 8 cases (47%) in PSP-RS group and in one case (10%) with PNFA. Perseverative errors did not differentiate between the groups.
ConclusionsAs omission errors predominate in writing of patients with PSP-RS, writing seems to be compromised mainly because of oculomotor deficits, that may alter visual feedback while writing.
Abstract
The overlap between progressive supranuclear palsy (PSP) and progressive non-fluent aphasia (PNFA) is being increasingly recognized. In this paper descriptive writing in patients with Richardson syndrome of progressive supranuclear palsy (PSP-RS) is compared to writing samples from patients with PNFA.
MethodsTwenty-seven patients participated in the study: 17 with the clinical diagnosis of PSP-RS and 10 with PNFA. Untimed written picture description was administered during neuropsychological assessment and subsequently scored by two raters blinded to the clinical diagnosis. Lexical and syntactic content, as well as writing errors (e.g. omission and perseverative errors) were analyzed.
ResultsIn patients with PSP-RS both letter and diacritic mark omission errors were very frequent. Micrographia was present in 8 cases (47%) in PSP-RS group and in one case (10%) with PNFA. Perseverative errors did not differentiate between the groups.
ConclusionsAs omission errors predominate in writing of patients with PSP-RS, writing seems to be compromised mainly because of oculomotor deficits, that may alter visual feedback while writing.
Keywords
Progressive supranuclear palsy, Primary progressive aphasia, Writing, Agraphia
About this articleTitle
Writing in Richardson variant of progressive supranuclear palsy in comparison to progressive non-fluent aphasia
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
217-222
Page views
231
Article views/downloads
376
DOI
10.1016/j.pjnns.2015.05.004
Bibliographic record
Neurol Neurochir Pol 2015;49(4):217-222.
Keywords
Progressive supranuclear palsy
Primary progressive aphasia
Writing
Agraphia
Authors
Emilia J. Sitek
Anna Barczak
Klaudia Kluj-Kozłowska
Marcin Kozłowski
Ewa Narożańska
Agnieszka Konkel
Magda Dąbrowska
Maria Barcikowska
Jarosław Sławek
