open access
Multiple atypical recurrent meningiomas 13 years after radiotherapy for unilateral retinoblastoma: case report and review of the literature
- Department of Neurosurgery, Istanbul School of Medicine, Istanbul University, Istanbul, Türkiye
- Institute of Oncology, Istanbul School of Medicine, Istanbul University, Istanbul, Türkiye
open access
Abstract
Radiotherapy is an important treatment modality for intracranial malignancies. Improved survival rates were achieved via a combination of surgery, chemotherapy and radiotherapy. On the other hand, improved survival rates made long-term complications of radiotherapy more apparent. Secondary neoplasms due to cranial irradiation are encountered more commonly in neurosurgical practice. Radiation-induced meningiomas are recognized as a common late complication of radiotherapy. However, radiation-induced meningiomas after radiotherapy for retinoblastoma have been reported rarely. Herein we report a patient who harboured multiple meningiomas 13 years after radiotherapy for unilateral retinoblastoma, which were recurrent despite surgical removal and chemotherapy.
Abstract
Radiotherapy is an important treatment modality for intracranial malignancies. Improved survival rates were achieved via a combination of surgery, chemotherapy and radiotherapy. On the other hand, improved survival rates made long-term complications of radiotherapy more apparent. Secondary neoplasms due to cranial irradiation are encountered more commonly in neurosurgical practice. Radiation-induced meningiomas are recognized as a common late complication of radiotherapy. However, radiation-induced meningiomas after radiotherapy for retinoblastoma have been reported rarely. Herein we report a patient who harboured multiple meningiomas 13 years after radiotherapy for unilateral retinoblastoma, which were recurrent despite surgical removal and chemotherapy.
Keywords
radiotherapy, meningioma, radiation-induced tumour, secondary brain neoplasms in children, retinoblastoma
Title
Multiple atypical recurrent meningiomas 13 years after radiotherapy for unilateral retinoblastoma: case report and review of the literature
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
1-6
Page views
368
Article views/downloads
599
DOI
10.5114/ninp.2013.32932
Bibliographic record
Neurol Neurochir Pol 2013;47(1):1-6.
Keywords
radiotherapy
meningioma
radiation-induced tumour
secondary brain neoplasms in children
retinoblastoma
Authors
Yavuz Aras
Mehmet Osman Akcakaya
Aydin Aydoseli
Rasim Meral
Talat Kiris