Vol 2, No 4 (2017)
Case report
Published online: 2018-03-30
A massive gross haematuria in an 85-year-old patient with acquired haemophilia A
Medical Research Journal 2017;2(4):178-180.
Abstract
The authors herein present a case report of an 85-year-old female patient with massive gross haematuria in the course of acquired haemophilia A. Acquired haemophilia in the geriatric population is a rare but severe bleeding disorder. It is caused by suddenly appearing autoantibodies that interfere with coagulation factor VIII activity. The diagnosis of acquired haemophilia should be considered in any patient who presents with bleeding and a prolonged activated partial thromboplastin time (APTT).
Keywords: haematuriahaemophiliaacquired haemophilia
References
- Fischer K, Hermans C. European Haemophilia Therapy Standardisation Board. The European Principles of Haemophilia Care: a pilot investigation of adherence to the principles in Europe. Haemophilia. 2013; 19(1): 35–43.
- Narodowy Program Leczenia Chorych na Hemofilię i Pokrewne Skazy Krwotoczne na lata 2012-2018. Minister Zdrowia, Warszawa 2013. . www.mz.gov.pl/zdrowie-i-profilaktyka/krwiodawstwo/program-zdrowotny-narodowy-program-leczenia-chorych-na-hemofilie-i-pokrewne-skazy-krwotoczne-na-lata-2012-2018/.
- Charakterystyka Produktu Leczniczego Pradaxa 110/150 mg. http://leki.urpl.gov.pl/files/25_PRADAXA_kap_tw.pdf.
- Castellone DD, Van Cott EM. Laboratory monitoring of new anticoagulants. Am J Hematol. 2010; 85(3): 185–187.
- Hosier GW, Mason RJ, Sue Robinson K, et al. Acquired hemophilia A: A rare cause of gross hematuria. Can Urol Assoc J. 2015; 9(11-12): E905–E907.
- Duran-Suarez JR. Incidence of circulating anticoagulants in a normal population. Acta Haematol. 1982; 67(3): 217–219.
- Green D, Lechner K. A survey of 215 non-hemophilic patients with inhibitors to Factor VIII. Thromb Haemost. 1981; 45(3): 200–203.