open access

Vol 2, No 4 (2017)
CASE REPORTS
Published online: 2018-03-30
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A massive gross haematuria in an 85-year-old patient with acquired haemophilia A

Katarzyna Mądra-Gackowska, Sylwia Ziółkowska, Marcin Gackowski, Emilia Główczewska-Siedlecka, Joanna Książak, Barbara Kaźmierczak, Kornelia Kędziora-Kornatowska
DOI: 10.5603/MRJ.2017.0025
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Medical Research Journal 2017;2(4):178-180.

open access

Vol 2, No 4 (2017)
CASE REPORTS
Published online: 2018-03-30

Abstract

The authors herein present a case report of an 85-year-old female patient with massive gross haematuria in the course of acquired haemophilia A. Acquired haemophilia in the geriatric population is a rare but severe bleeding disorder. It is caused by suddenly appearing autoantibodies that interfere with coagulation factor VIII activity. The diagnosis of acquired haemophilia should be considered in any patient who presents with bleeding and a prolonged activated partial thromboplastin time (APTT).

Abstract

The authors herein present a case report of an 85-year-old female patient with massive gross haematuria in the course of acquired haemophilia A. Acquired haemophilia in the geriatric population is a rare but severe bleeding disorder. It is caused by suddenly appearing autoantibodies that interfere with coagulation factor VIII activity. The diagnosis of acquired haemophilia should be considered in any patient who presents with bleeding and a prolonged activated partial thromboplastin time (APTT).

Get Citation

Keywords

haematuria, haemophilia, acquired haemophilia

About this article
Title

A massive gross haematuria in an 85-year-old patient with acquired haemophilia A

Journal

Medical Research Journal

Issue

Vol 2, No 4 (2017)

Pages

178-180

Published online

2018-03-30

DOI

10.5603/MRJ.2017.0025

Bibliographic record

Medical Research Journal 2017;2(4):178-180.

Keywords

haematuria
haemophilia
acquired haemophilia

Authors

Katarzyna Mądra-Gackowska
Sylwia Ziółkowska
Marcin Gackowski
Emilia Główczewska-Siedlecka
Joanna Książak
Barbara Kaźmierczak
Kornelia Kędziora-Kornatowska

References (7)
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  2. Narodowy Program Leczenia Chorych na Hemofilię i Pokrewne Skazy Krwotoczne na lata 2012-2018. Minister Zdrowia, Warszawa 2013. . www.mz.gov.pl/zdrowie-i-profilaktyka/krwiodawstwo/program-zdrowotny-narodowy-program-leczenia-chorych-na-hemofilie-i-pokrewne-skazy-krwotoczne-na-lata-2012-2018/.
  3. Charakterystyka Produktu Leczniczego Pradaxa 110/150 mg. http://leki.urpl.gov.pl/files/25_PRADAXA_kap_tw.pdf.
  4. Castellone DD, Van Cott EM. Laboratory monitoring of new anticoagulants. Am J Hematol. 2010; 85(3): 185–187.
  5. Hosier GW, Mason RJ, Sue Robinson K, et al. Acquired hemophilia A: A rare cause of gross hematuria. Can Urol Assoc J. 2015; 9(11-12): E905–E907.
  6. Duran-Suarez JR. Incidence of circulating anticoagulants in a normal population. Acta Haematol. 1982; 67(3): 217–219.
  7. Green D, Lechner K. A survey of 215 non-hemophilic patients with inhibitors to Factor VIII. Thromb Haemost. 1981; 45(3): 200–203.

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