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Vol 7, No 4 (2022)
Review article
Published online: 2022-11-22

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Granulocyte transfusion vs. neutropenia — is there a chance to win this battle?

Artur Szumowski12, Piotr Marek Radziwon12
DOI: 10.5603/MRJ.a2022.0048
Medical Research Journal 2022;7(4):321-332.

Abstract

Bacterial and fungal infections remain a significant cause of morbidity and mortality in patients with prolonged severe neutropenia that results from the treatment of an underlying haematological malignancy. Granulocyte transfusions have been broadly used to prevent and/or treat life-threatening infections in these patients. The purpose of this review was to answer the question, “Are granulocyte transfusions effective in combating hazardous infections in haematology/oncology patients with neutropenia?”.

Keywords: haematological malignancyneutropeniabacterial infectionfungal infectionleukapheresisgranulocyte transfusion

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