Two different approaches to assess adherence to medication in Polish cohort of the EUROASPIRE V registry
, 1, 2, 1, 2, 3, 4, 56
Abstract
Introduction: The implementation of guidelines on cardiovascular disease (CVD) prevention in patients at
high risk of developing CVD was assessed in the EUROASPIRE V registry.
Aim of the study: This study was designed to compare a simple self-reported quantitative assessment of
adherence to medication using the Medication Adherence Questionnaire (MAQ) with a qualitative evaluation
based on the Adherence in Chronic Disease Scale (ACDS) in the Polish cohort of the EUROSPIRE V registry.
Material and methods: The study was performed in 200 patients (133 women and 67 men) with an average
age of 51.49 (13.63) years and a history of hypertension, hypercholesterolemia or diabetes, but without prior
cardiovascular events. Pharmacological treatment was applied in 127 patients (63.5%) with hypertension,
90 (45%) with hypercholesterolemia, and 31 (15.5%) with diabetes.
Results: According to the MAQ, high adherence to medication (100% or 90%) was declared by 67.7%
of patients, while medium (75% or 50%) and low adherence (< 50% or 0%) by 9.7% and 22.6%, respectively.
The adherence assessed with the ACDS, was high in 38.7%, medium in 44.8%, and low in 16.5%
of patients. A remarkable inconsistency between ACDS and MAQ responses was found. The MAQ and
the ACDS rendered consistent results in 44.8% of patients (111 out of 148), while in the remaining 55.2%
(137 out of 248) of patients the results were discordant.
Conclusions: The assessment of medication adherence based on patient declarations used in the EUROASPIRE
V registry is likely to overestimate the frequency of high adherence.
Keywords: Adherence to medicationhypertensiondiabeteshypercholesterolemia
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