Vol 5, No 1 (2020)
Original article
Published online: 2020-02-26

open access

Page views 840
Article views/downloads 655
Get Citation

Connect on Social Media

Connect on Social Media

The influence of obesity on in-hospital clinical outcomes after recanalisation of chronic total occlusions

Ali Aldujeli1, Kasparas Briedis2, Paulina Simaityte3, Montazar Aldujeili4, Rima Braukyliene1, Ramunas Unikas1
Medical Research Journal 2020;5(1):19-22.

Abstract

Objectives: Recanalisation of chronic total occlusions (CTOs) in interventional cardiology is one of the most challenging and complex procedures. Currently, no data are available about the impact of BMI on success rates among CTO patients undergoing percutaneous coronary intervention. The aim of this study was to investigate the impact that BMI has on success rates, complications, and procedure characteristics among a large group of CTO patients who underwent percutaneous coronary intervention.

Methods:
The present study retrospectively included 420 patients who underwent percutaneous coronary intervention for at least one chronic total occlusion in the Hospital of the Lithuanian University of Health Sciences of Kaunas. All patients were grouped by their BMI level based on the World Health Organisation classification. Statistical analyses were performed using SPSS 20.0 software. The value of p < 0.05 was considered as statistically significant.

Results:
Positive correlations were detected between body mass index and cardiovascular risk factors, as well as the duration of the procedure and fluoroscopy time; likewise, the amount of used contrast increased with the increase of BMI (p < 0.05). Nevertheless, there was no statistically significant difference across all body mass index categories in terms of procedure success, complication rates, and outcomes (p > 0.05).

Conclusion:
This retrospective study indicates that BMI has no impact on in-hospital outcomes in patients with chronic total occlusion after percutaneous coronary intervention.

Article available in PDF format

View PDF Download PDF file

References

  1. Konstantinidis N, Pighi M, Dogu Kilic I, et al. New Advances in Chronic Total Occlusions. Interv Cardiol. 2014; 9(3): 208–212.
  2. Fefer P, Knudtson ML, Cheema AN, et al. Current perspectives on coronary chronic total occlusions: the Canadian Multicenter Chronic Total Occlusions Registry. J Am Coll Cardiol. 2012; 59(11): 991–997.
  3. Rawlins J, Wilkinson J, Curzen N. Evidence for Benefit of Percutaneous Coronary Intervention for Chronically Occluded Coronary Arteries (CTO) - Clinical and Health Economic Outcomes. Interv Cardiol. 2014; 9(3): 190–194.
  4. Chimura M, Yamada S, Yasaka Y, et al. Improvement of left ventricular function assessment by global longitudinal strain after successful percutaneous coronary intervention for chronic total occlusion. PLoS One. 2019; 14(6): e0217092.
  5. Gülker JE, Bansemir L, Klues HG, et al. Chronic total coronary occlusion recanalization: Current techniques and new devices. J Saudi Heart Assoc. 2017; 29(2): 110–115.
  6. Shah A. Chronic Total Occlusion Coronary Intervention: In Search of a Definitive Benefit. Methodist Debakey Cardiovasc J. 2018; 14(1): 50–59.
  7. Agha M, Agha R. The rising prevalence of obesity: part A: impact on public health. Int J Surg Oncol (N Y). 2017; 2(7): e17.
  8. Akil L, Ahmad HA. Relationships between obesity and cardiovascular diseases in four southern states and Colorado. J Health Care Poor Underserved. 2011; 22(4 Suppl): 61–72.
  9. Chen Yu, Copeland WK, Vedanthan R, et al. Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort Consortium. BMJ. 2013; 347: f5446.
  10. Bucholz EM, Rathore SS, Reid KJ, et al. Body mass index and mortality in acute myocardial infarction patients. Am J Med. 2012; 125(8): 796–803.
  11. Christopoulos G, Wyman RM, Alaswad K, et al. Clinical Utility of the Japan-Chronic Total Occlusion Score in Coronary Chronic Total Occlusion Interventions: Results from a Multicenter Registry. Circ Cardiovasc Interv. 2015; 8(7): e002171.
  12. Kotnis-Gąska A, Mazur P, Olechowska-Jarząb A, et al. Sternal wound infections following cardiac surgery and their management: a single-centre study from the years 2016-2017. Kardiochir Torakochirurgia Pol. 2018; 15(2): 79–85.
  13. Kadakia MB, Fox CS, Scirica BM, et al. Central obesity and cardiovascular outcomes in patients with acute coronary syndrome: observations from the MERLIN-TIMI 36 trial. Heart. 2011; 97(21): 1782–1787.
  14. Lai CC, Wei KC, Chen WY, et al. Risk Factors For Radiation-Induced Skin Ulceration in Percutaneous Coronary Interventions of Chronic Total Occluded Lesions: A 2-Year Observational Study. Sci Rep. 2017; 7(1): 8408.
  15. Patel N, Elsaid O, Shenoy A, et al. Obesity paradox in patients undergoing coronary intervention: A review. World J Cardiol. 2017; 9(9): 731–736.
  16. Won KB, Yoon HJ, Lee SG, et al. Comparison of long-term mortality according to obesity in patients with successful percutaneous chronic total occlusion interventions using drug-eluting stents. Catheter Cardiovasc Interv. 2018; 91(4): 710–716.
  17. Stähli BE, Gebhard C, Gick M, et al. Impact of body mass index on long-term mortality in women and men undergoing percutaneous coronary intervention for chronic total occlusion. Int J Cardiol. 2016; 224: 305–309.
  18. Diletti R, Garcia-Garcia HM, Bourantas C, et al. Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program. Catheter Cardiovasc Interv. 2015; 85(6): 952–958.
  19. Hällberg V, Kataja M, Lahtela J, et al. W-CABG Study Group. Obesity paradox disappears in coronary artery bypass graft patients during 20-year follow-up. Eur Heart J Acute Cardiovasc Care. 2017; 6(8): 771–777.
  20. Benderly M, Boyko V, Goldbourt U. Relation of body mass index to mortality among men with coronary heart disease. Am J Cardiol. 2010; 106(3): 297–304.