Vol 2, No 4 (2017)
Original article
Published online: 2018-03-30

open access

Page views 888
Article views/downloads 1036
Get Citation

Connect on Social Media

Connect on Social Media

Bacterial spectrum of orofacial infections and their antibiotic resistance in Belarus

Arina Kabanova1
Medical Research Journal 2017;2(4):152-156.

Abstract

The purpose of the present study was to was to determine the pathogenic bacterial spectrum and bacterial antibiotic resistance in maxillofacial region of Belarussian patients.

Materials and methods. The study comprised inpatient who were treated by maxillofacial surgeons during 2014 in hospitals of Belarussian region: Brest, Mogilev, Vitebsk, Grodno and Gomel. It was a retrospec-tive study, approval by the institution ethical committee. A microbiological sample was collected before antibiotic treatment. After meticulous disinfection of the skin around the planned extraoral incision site the aspiration of pus was attempted. If aspiration cannot be conducted, the samples were collected by swabbing the area after the incision and discharge of the pus. After sample collection, the material was immediately transported to the laboratory and further processed within 2 hours at the most. All speci-mens were then tested for the prevalence of the predominant bacteria and their antibiotic susceptibility Results. At the present stage in Belarussian hospitals the main agents isolating from inflammatory fo-cus of the maxillofacial region are streptococci, staphylococci, enterobacteria, that corresponds with the global data. On the basis of the major pathogen antibiotic resistance data the following antibiotics for initial therapy until the receiving the results of bacteriological tests can be recommended: clinda-mycin (effective against all studied pathogenic species), ceftriaxone, fluoroquinolones (ciprofloxacin).

Conclusions. It is necessary to conduct further systematic monitoring of microflora in patients with inflam-matory diseases of maxillofacial area and studding the bacteria antibiotic resistance in order to improve the patient treatment efficiency.

Article available in PDF format

View PDF Download PDF file

References

  1. Pinelis IS. Turchina YeV. Modern views on antibacterial therapy of pуо-inflammatory diseases of maxillofacial area. The Transbaikalian Medical Bulletin. 2014; 3: 182–188.
  2. Tsarev VN. Nikolayeva YeN, Sarkisyan NA. Detection of periodontopathogenic bacterial markers in patients with infective endocarditis. Russian Dental Journal. 2009; 2: 32–34.
  3. Keijser BJF, Zaura E, Huse SM, et al. Pyrosequencing analysis of the oral microflora of healthy adults. J Dent Res. 2008; 87(11): 1016–1020.
  4. Bahl R, Sandhu S, Singh K, et al. Odontogenic infections: Microbiology and management. Contemp Clin Dent. 2014; 5(3): 307–311.
  5. Avila M, Ojcius DM, Yilmaz O. The oral microbiota: living with a permanent guest. DNA Cell Biol. 2009; 28(8): 405–411.
  6. Timofeyev AA, Dakal AV, Kishkovskaya YN. Clinical flow of оdontogenic inflammatory diseases of jaws and soft tissues for an ill with narcomania. Modern dentistry. 2009; 1: 94–98.
  7. Kovaleva N, Zuzova AP. Pyoinflammatory Diseases Of The Maxillofacial Area: Aspects Of The Clinic, Microbiology, And Pharmacotherapy. Farmateka. 2011; 8: 34–38.
  8. Götz C, Reinhart E, Wolff KD, et al. Oral soft tissue infections: causes, therapeutic approaches and microbiological spectrum with focus on antibiotic treatment. J Craniomaxillofac Surg. 2015; 43(9): 1849–1854.
  9. Skala LZ, Sidorenko SV, Nekhorosheva AG, et al. Practical aspects of modern clinical microbiology: Triada. ; 2004: 310.
  10. Clinical and Laboratory Standard Institute. Performance Standards for Antimicrobial Susceptibility Testing, Nineteenth Informational Supplement M100-S18, Vol. 28, No. 1. Wayne, PA: CLSI. : 2008.
  11. Poeschl PW, Crepaz V, Russmueller G, et al. Endodontic pathogens causing deep neck space infections: clinical impact of different sampling techniques and antibiotic susceptibility. J Endod. 2011; 37(9): 1201–1205.
  12. Rebrova OYu. Statistical analysis of medical data. The use of the application package STATISTICA: MediaSfera. ; 2002: 212.
  13. Bogatov BB, Denis AG, Koliadov NF. [Rational antimicrobial therapy in patients with purulent inflammatory diseases of maxillofacial area]. Stomatologiia (Mosk). 2015; 94(1): 37–39.