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Histopathological Types of Operable Early Breast Cancer in the Elderly: Is there a Special Pattern? – a Retrospective, Multicentre Study
Affiliations- Basildon & Thurrock University Hospital, Nethermayne, Basildon, Essex, United Kingdom
- Greater Poland Oncology Centre, ul.Garbary 15, 61-866 Poznan, Poland
- Department of General , Endocrine and Gastroenterological Surgery, ul.Przybyszewskiego 49, 60-355 Poznan, Poland
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Abstract
Introduction: The aim of this study was to determine the pattern of histopathological types of breast cancer in women aged 70 years or more with operable early breast cancer, and its implication on the potential prognosis. Methodology & Material: A retrospective cohort study included 170 patients hospitalised for breast cancer treatment in departments of surgery of two teaching hospitals (Basildon University Hospital, Basildon, United Kingdom, and Greater Poland Oncology Centre, Poznan, Poland).
Material and methods: All 170 patients underwent surgical management for breast cancer. Invasive ductal carcinoma (IDC) was the most common histopathological type in the study group (74%). The mucinous carcinoma was seen in 1.7% of cases, invasive lobular carcinoma in only 1% of patients, while the ductal carcinoma in situ was present in 6.5% of subjects. Lympho-vascular invasion was detected in 23% of cases.
Conclusion: Less aggressive histological pattern was predominantly detected in the elderly patients with breast cancers.
Abstract
Introduction: The aim of this study was to determine the pattern of histopathological types of breast cancer in women aged 70 years or more with operable early breast cancer, and its implication on the potential prognosis. Methodology & Material: A retrospective cohort study included 170 patients hospitalised for breast cancer treatment in departments of surgery of two teaching hospitals (Basildon University Hospital, Basildon, United Kingdom, and Greater Poland Oncology Centre, Poznan, Poland).
Material and methods: All 170 patients underwent surgical management for breast cancer. Invasive ductal carcinoma (IDC) was the most common histopathological type in the study group (74%). The mucinous carcinoma was seen in 1.7% of cases, invasive lobular carcinoma in only 1% of patients, while the ductal carcinoma in situ was present in 6.5% of subjects. Lympho-vascular invasion was detected in 23% of cases.
Conclusion: Less aggressive histological pattern was predominantly detected in the elderly patients with breast cancers.
Keywords
Breast cancer, ductal carcinoma, lobular carcinoma, mucinous carcinoma, lympho-vascular invasion
About this articleTitle
Histopathological Types of Operable Early Breast Cancer in the Elderly: Is there a Special Pattern? – a Retrospective, Multicentre Study
Journal
Issue
Article type
Original article
Pages
10-14
Published online
2018-03-20
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1045
Article views/downloads
1055
DOI
Bibliographic record
Medical Research Journal 2018;3(1):10-14.
Keywords
Breast cancer
ductal carcinoma
lobular carcinoma
mucinous carcinoma
lympho-vascular invasion
Authors
Abdalla Saad Abdalla Al-Zawi
Beata Adamczyk
Anna Wejman-Matela
Sharlini Sathananthan
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