open access

Vol 80, No 12 (2022)
Review paper
Published online: 2022-12-02
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Transcatheter edge-to-edge repair in acute mitral regurgitation following acute myocardial infarction: Recent advances

Dan Haberman1, Shani Dahan2, Lion Poles1, David Marmor3, Mony Shuvy3
DOI: 10.33963/KP.a2022.0276
·
Pubmed: 36621015
·
Kardiol Pol 2022;80(12):1190-1199.
Affiliations
  1. Heart Center, Kaplan Medical Center, Rehovot, Israel; Affiliated with the Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem, Israel
  2. Department of Cardiology, Assuta Ashdod Medical Center; Affiliated to the Ben Gurion University of the Negev, Ashdod, Israel
  3. Jesselson Integrated Heart Centre, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel

open access

Vol 80, No 12 (2022)
Review article
Published online: 2022-12-02

Abstract

Acute mitral regurgitation (MR) is not a rare finding following acute myocardial infarction (AMI). It may develop due to papillary muscle rupture (primary MR) or due to rapid remodeling of the infarcted areas leading to geometric changes and leaflets tethering (secondary or functional MR). The clinical presentation can be catastrophic, with pulmonary edema and refractory cardiogenic shock. Acute MR is a potentially life-threatening complication and is linked to worse clinical outcomes. Until recently, medical treatment or mitral valve surgery were the only established treatment options for these patients. However, there is growing evidence for the benefits of safe and effective trans-catheter interventions in this condition, specifically transcatheter edge-to-edge repair (TEER). We aimed to review the current role of TEER in post-MI acute MR patients, focusing on different etiologies.

Abstract

Acute mitral regurgitation (MR) is not a rare finding following acute myocardial infarction (AMI). It may develop due to papillary muscle rupture (primary MR) or due to rapid remodeling of the infarcted areas leading to geometric changes and leaflets tethering (secondary or functional MR). The clinical presentation can be catastrophic, with pulmonary edema and refractory cardiogenic shock. Acute MR is a potentially life-threatening complication and is linked to worse clinical outcomes. Until recently, medical treatment or mitral valve surgery were the only established treatment options for these patients. However, there is growing evidence for the benefits of safe and effective trans-catheter interventions in this condition, specifically transcatheter edge-to-edge repair (TEER). We aimed to review the current role of TEER in post-MI acute MR patients, focusing on different etiologies.

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Keywords

mitral regurgitation, myocardial infarction, cardiogenic shock, papillary muscle rupture, trans-catheter edge-to-edge repair

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Title

Transcatheter edge-to-edge repair in acute mitral regurgitation following acute myocardial infarction: Recent advances

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 80, No 12 (2022)

Article type

Review paper

Pages

1190-1199

Published online

2022-12-02

Page views

551

Article views/downloads

118

DOI

10.33963/KP.a2022.0276

Pubmed

36621015

Bibliographic record

Kardiol Pol 2022;80(12):1190-1199.

Keywords

mitral regurgitation
myocardial infarction
cardiogenic shock
papillary muscle rupture
trans-catheter edge-to-edge repair

Authors

Dan Haberman
Shani Dahan
Lion Poles
David Marmor
Mony Shuvy

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