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Review paper
Published online: 2022-05-02
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Cerebral embolic protection in patients undergoing transcatheter aortic valve implantation: Recent advances

Ines Richter1, Mohamed Abdel-Wahab1, Steffen Desch1, Holger Thiele1
DOI: 10.33963/KP.a2022.0118
·
Pubmed: 35521720
Affiliations
  1. Heart Center Leipzig at University of Leipzig, Leipzig, Germany

open access

Online first
Review
Published online: 2022-05-02

Abstract

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Abstract

Not available
Get Citation
About this article
Title

Cerebral embolic protection in patients undergoing transcatheter aortic valve implantation: Recent advances

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Online first

Article type

Review paper

Published online

2022-05-02

Page views

97

Article views/downloads

29

DOI

10.33963/KP.a2022.0118

Pubmed

35521720

Authors

Ines Richter
Mohamed Abdel-Wahab
Steffen Desch
Holger Thiele

References (28)
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  2. Demir OM, Iannopollo G, Mangieri A, et al. The role of cerebral embolic protection devices during transcatheter aortic valve replacement. Front Cardiovasc Med. 2018; 5: 150.
  3. Kapadia S, Agarwal S, Miller DC, et al. Insights into timing, risk factors, and outcomes of stroke and transient ischemic attack after transcatheter aortic valve replacement in the PARTNER trial (placement of aortic transcatheter valves). Circ Cardiovasc Interv. 2016; 9(9): e002981.
  4. Kahlert P, Knipp SC, Schlamann M, et al. Silent and apparent cerebral ischemia after percutaneous transfemoral aortic valve implantation: a diffusion-weighted magnetic resonance imaging study. Circulation. 2010; 121(7): 870–878.
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  8. Kapadia SR, Kodali S, Makkar R, et al. SENTINEL Trial Investigators. Protection against cerebral embolism during transcatheter aortic valve replacement. J Am Coll Cardiol. 2017; 69(4): 367–377.
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  10. Van Mieghem NM, van Gils L, Ahmad H, et al. Filter-based cerebral embolic protection with transcatheter aortic valve implantation: the randomised MISTRAL-C trial. EuroIntervention. 2016; 12(4): 499–507.
  11. Lansky AJ, Schofer J, Tchetche D, et al. A prospective randomized evaluation of the TriGuard™ HDH embolic DEFLECTion device during transcatheter aortic valve implantation: results from the DEFLECT III trial. Eur Heart J. 2015; 36(31): 2070–2078.
  12. Lansky A. A patient level pooled analysis of neuroprotection with the triguard embolic deflection device compared to unprotected transcatheter aortic valve replacement 2016.
  13. Lansky AJ, Makkar R, Nazif T, et al. A randomized evaluation of the TriGuard™ HDH cerebral embolic protection device to Reduce the Impact of Cerebral Embolic LEsions after TransCatheter Aortic Valve ImplanTation: the REFLECT I trial. Eur Heart J. 2021; 42(27): 2670–2679.
  14. Nazif TM, Moses J, Sharma R, et al. REFLECT II Trial Investigators. Randomized evaluation of triguard 3 cerebral embolic protection after transcatheter aortic valve replacement: REFLECT II. JACC Cardiovasc Interv. 2021; 14(5): 515–527.
  15. Rodés-Cabau J, Kahlert P, Neumann FJ, et al. Feasibility and exploratory efficacy evaluation of the Embrella Embolic Deflector system for the prevention of cerebral emboli in patients undergoing transcatheter aortic valve replacement: the PROTAVI-C pilot study. JACC Cardiovasc Interv. 2014; 7(10): 1146–1155.
  16. Wendt D, Kleinbongard P, Knipp S, et al. Intraaortic protection from embolization in patients undergoing transaortic transcatheter aortic valve implantation. Ann Thorac Surg. 2015; 100(2): 686–691.
  17. Leon MB, Smith CR, Mack MJ, et al. PARTNER 2 Investigators. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med. 2016; 374(17): 1609–1620.
  18. Messé SR, Acker MA, Kasner SE, et al. Determining Neurologic Outcomes from Valve Operations (DeNOVO) Investigators. Stroke after aortic valve surgery: results from a prospective cohort. Circulation. 2014; 129(22): 2253–2261.
  19. Généreux P, Piazza N, Alu MC, et al. VARC-3 WRITING COMMITTEE. Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research. Eur Heart J. 2021; 42(19): 1825–1857.
  20. Erdoes G, Basciani R, Huber C, et al. Transcranial Doppler-detected cerebral embolic load during transcatheter aortic valve implantation. Eur J Cardiothorac Surg. 2012; 41(4): 778–784.
  21. Woldendorp K, Indja B, Bannon PG, et al. Silent brain infarcts and early cognitive outcomes after transcatheter aortic valve implantation: a systematic review and meta-analysis. Eur Heart J. 2021; 42(10): 1004–1015.
  22. Vermeer SE, Prins ND, den Heijer T, et al. Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med. 2003; 348(13): 1215–1222.
  23. Auffret V, Regueiro A, Del Trigo M, et al. Predictors of early cerebrovascular events in patients with aortic stenosis undergoing transcatheter aortic valve replacement. J Am Coll Cardiol. 2016; 68(7): 673–684.
  24. Kroon H, von der Thusen JH, Ziviello F, et al. Heterogeneity of debris captured by cerebral embolic protection filters during TAVI. EuroIntervention. 2021; 16(14): 1141–1147.
  25. Van Mieghem NM, Schipper MEI, Ladich E, et al. Histopathology of embolic debris captured during transcatheter aortic valve replacement. Circulation. 2013; 127(22): 2194–2201.
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  27. Testa L, Latib A, Brambilla N, et al. Long-term clinical outcome and performance of transcatheter aortic valve replacement with a self-expandable bioprosthesis. Eur Heart J. 2020; 41(20): 1876–1886.
  28. Kahlert P, Al-Rashid F, Döttger P, et al. Cerebral embolization during transcatheter aortic valve implantation: a transcranial Doppler study. Circulation. 2012; 126(10): 1245–1255.

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