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Predictors of COVID-19 outcomes in adult congenital heart disease patients — anatomy versus function
Affiliations- Department of Congenital Heart Disease, National Institute of Cardiology, Warszawa, Poland
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Abstract
Background: It is unclear whether patients with adult congenital heart disease (ACHD) should be considered as an increased risk population with poor outcomes when suffering from COVID-19.
Aims: This study aimed to collect clinical outcome data and to identify risk factors of a complicated course of COVID-19 among ACHD patients.
Methods: Among all outpatients who came to medical attention via telemedicine or direct physician contact at our institution between September 1, 2020 and March 31, 2021, we included all with a COVID-19 diagnosis. The incidence of COVID-19, a clinical course of the disease, and outcome were determined.
Results: One hundred and four (8.7%) out of 1 197 patients who were seen at our outpatient clinic for ACHD patients met the definition of COVID-19. Most of them reported a mild course of COVID-19 (99 [95.5%]). Five patients (4.5%) experienced severe symptoms and needed hospitalization. Two patients (1.9% of all with a confirmed diagnosis, 40% with severe infection) died. In the multivariable analysis, decreased systemic ventricular systolic function and any significant valve stenosis were predictors of a complicated disease course.
Conclusions: Our study confirmed previous results showing that a physiology-based model, rather than an anatomy-based model, better predicted COVID-19 outcomes among ACHD patients, which is of importance for patients and healthcare providers during the COVID-19 pandemic.
Abstract
Background: It is unclear whether patients with adult congenital heart disease (ACHD) should be considered as an increased risk population with poor outcomes when suffering from COVID-19.
Aims: This study aimed to collect clinical outcome data and to identify risk factors of a complicated course of COVID-19 among ACHD patients.
Methods: Among all outpatients who came to medical attention via telemedicine or direct physician contact at our institution between September 1, 2020 and March 31, 2021, we included all with a COVID-19 diagnosis. The incidence of COVID-19, a clinical course of the disease, and outcome were determined.
Results: One hundred and four (8.7%) out of 1 197 patients who were seen at our outpatient clinic for ACHD patients met the definition of COVID-19. Most of them reported a mild course of COVID-19 (99 [95.5%]). Five patients (4.5%) experienced severe symptoms and needed hospitalization. Two patients (1.9% of all with a confirmed diagnosis, 40% with severe infection) died. In the multivariable analysis, decreased systemic ventricular systolic function and any significant valve stenosis were predictors of a complicated disease course.
Conclusions: Our study confirmed previous results showing that a physiology-based model, rather than an anatomy-based model, better predicted COVID-19 outcomes among ACHD patients, which is of importance for patients and healthcare providers during the COVID-19 pandemic.
Keywords
COVID-19 infection, adult congenital heart disease, outcome
About this articleTitle
Predictors of COVID-19 outcomes in adult congenital heart disease patients — anatomy versus function
Journal
Kardiologia Polska (Polish Heart Journal)
Issue
Article type
Original article
Pages
151-155
Published online
2021-12-09
Page views
4264
Article views/downloads
493
DOI
10.33963/KP.a2021.0176
Pubmed
Bibliographic record
Kardiol Pol 2022;80(2):151-155.
Keywords
COVID-19 infection
adult congenital heart disease
outcome
Authors
Magdalena Lipczyńska
Ewa Kowalik
Magdalena Kumor
Beata Kuśmierczyk-Droszcz
Anna W Wójcik
Elżbieta K Biernacka
Piotr Hoffman
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