open access

Vol 72, No 6 (2014)
Original articles
Published online: 2014-06-11
Get Citation

The relationship between Gensini score and ST-segment resolution in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Aycan Esen Zencirci, Ertugrul Zencirci, Aleks Degirmencioglu, Gultekin Karakus, Murat Ugurlucan, Sabahattin Gunduz, Kivilcim Ozden, Aysun Erdem, Fatma Karadeniz, Ahmet Ekmekci, Hatice Erer, Nurten Sayar, Mehmet Eren
DOI: 10.5603/KP.a2013.0355
·
Kardiol Pol 2014;72(6):494-503.

open access

Vol 72, No 6 (2014)
Original articles
Published online: 2014-06-11

Abstract

Background: Clinical outcomes of patients with myocardial infarction are primarily determined by the successful restoration of myocardial reperfusion and the severity of coronary atherosclerosis.

Aim: To investigate the predictive value of Gensini score on ST-segment resolution (STR) in patients undergoing primary percutaneous coronary intervention (pPCI) for acute ST-elevation myocardial infarction (STEMI).

Methods: The present study prospectively included 114 consecutive patients (mean age 54 ± 10 years, 15 women) with STEMI who underwent successful pPCI. Sum of ST-segment elevation amount in millimetres was obtained before angioplastyand 60 min after pPCI. ΣSTR < 50% was accepted as a ECG sign of no-reflow phenomenon. Thrombus grading was calculated according to the results of coronary angiography, and Gensini score (GS-pPCI) was calculated after pPCI without incorporating culprit lesion. Patients were divided into two groups according to STR: those with STR(–), and those with STR(+). Patients were also analysed according to the infarct-related artery.

Results: GS-pPCI was significantly higher in patients with STR(–) (10.1 ± 11.8 vs. 22 ± 18.6, p = 0.005). GS-pPCI was inversely correlated with STR (r = –0.287, p = 0.002). In subgroup analysis, patients in the STR(–) group with culprit lesion in left anterior descending artery and left circumflex artery also showed higher GS-pPCI (10.9 ± 13.5 vs. 23.5 ± 21.3, p = 0.03 and 9.6 ± 8.7 vs. 24.1 ± 21, p = 0.04, respectively). High thrombus burden was also observed more frequently in patients with STR(–) (68% vs. 43%, p = 0.03). Multivariate logistic regression analysis demonstrated that GS-pPCI and high thrombus burden independently predicted inadequate STR (OR 1.07, 95% CI 1.03–1.12, p = 0.001 and OR 3.28, 95% CI1.11–9.72, p = 0.03, respectively).Conclusions: GS-pPCI and high thrombus burden play an important role in predicting inadequate STR in patients with STEMI treated with pPCI.

Abstract

Background: Clinical outcomes of patients with myocardial infarction are primarily determined by the successful restoration of myocardial reperfusion and the severity of coronary atherosclerosis.

Aim: To investigate the predictive value of Gensini score on ST-segment resolution (STR) in patients undergoing primary percutaneous coronary intervention (pPCI) for acute ST-elevation myocardial infarction (STEMI).

Methods: The present study prospectively included 114 consecutive patients (mean age 54 ± 10 years, 15 women) with STEMI who underwent successful pPCI. Sum of ST-segment elevation amount in millimetres was obtained before angioplastyand 60 min after pPCI. ΣSTR < 50% was accepted as a ECG sign of no-reflow phenomenon. Thrombus grading was calculated according to the results of coronary angiography, and Gensini score (GS-pPCI) was calculated after pPCI without incorporating culprit lesion. Patients were divided into two groups according to STR: those with STR(–), and those with STR(+). Patients were also analysed according to the infarct-related artery.

Results: GS-pPCI was significantly higher in patients with STR(–) (10.1 ± 11.8 vs. 22 ± 18.6, p = 0.005). GS-pPCI was inversely correlated with STR (r = –0.287, p = 0.002). In subgroup analysis, patients in the STR(–) group with culprit lesion in left anterior descending artery and left circumflex artery also showed higher GS-pPCI (10.9 ± 13.5 vs. 23.5 ± 21.3, p = 0.03 and 9.6 ± 8.7 vs. 24.1 ± 21, p = 0.04, respectively). High thrombus burden was also observed more frequently in patients with STR(–) (68% vs. 43%, p = 0.03). Multivariate logistic regression analysis demonstrated that GS-pPCI and high thrombus burden independently predicted inadequate STR (OR 1.07, 95% CI 1.03–1.12, p = 0.001 and OR 3.28, 95% CI1.11–9.72, p = 0.03, respectively).Conclusions: GS-pPCI and high thrombus burden play an important role in predicting inadequate STR in patients with STEMI treated with pPCI.

Get Citation

Keywords

acute myocardial infarction, Gensini score, ST-segment resolution, thrombus burden

About this article
Title

The relationship between Gensini score and ST-segment resolution in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 72, No 6 (2014)

Pages

494-503

Published online

2014-06-11

DOI

10.5603/KP.a2013.0355

Bibliographic record

Kardiol Pol 2014;72(6):494-503.

Keywords

acute myocardial infarction
Gensini score
ST-segment resolution
thrombus burden

Authors

Aycan Esen Zencirci
Ertugrul Zencirci
Aleks Degirmencioglu
Gultekin Karakus
Murat Ugurlucan
Sabahattin Gunduz
Kivilcim Ozden
Aysun Erdem
Fatma Karadeniz
Ahmet Ekmekci
Hatice Erer
Nurten Sayar
Mehmet Eren

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By VM Media Sp. z o.o. VM Group Sp.k., ul. Świętokrzyska 73 , 80–180 Gdańsk, Poland

phone:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: viamedica@viamedica.pl