open access

Vol 80, No 6 (2022)
Review paper
Published online: 2022-05-04
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Severe maternal morbidity and risk of cardiovascular disease: Recent advances

Ugochinyere Vivian Ukah12, Nathalie Auger1234
DOI: 10.33963/KP.a2022.0119
·
Pubmed: 35521721
·
Kardiol Pol 2022;80(6):638-643.
Affiliations
  1. Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada
  2. Institut national de santé publique du Québec, Montreal, Quebec, Canada
  3. University of Montreal Hospital Research Center, Montreal, Quebec, Canada
  4. Department of Social and Preventive Medicine, School of Public Health, University of Montreal, Montreal, Quebec, Canada

open access

Vol 80, No 6 (2022)
Review
Published online: 2022-05-04

Abstract

Pregnancy complications including severe maternal morbidity have been linked with an increased risk of cardiovascular disease, and provide opportunities to identify women who would benefit from prevention. Severe maternal morbidity comprises life-endangering complications around the time of pregnancy and delivery. Literature on the relationship between severe maternal morbidity and cardiovascular disease is increasing at a rapid pace. Studies have shown that severe preeclampsia or eclampsia and severe hemorrhage are associated with cardiovascular disease later in life. Proposed pathways include endothelial damage, hypercoagulability, and impaired cardiac function that are induced or exacerbated by severe pregnancy complications that elevate cardiovascular risks. However, less is known about other types of severe maternal morbidity that may influence the risk of cardiovascular disease. Other research gaps include a need to better understand the pathways and mechanisms linking severe maternal morbidity with cardiovascular disease, the potential for cardiovascular recovery after severe cardiovascular events during pregnancy, and disparities in the occurrence of cardiovascular disease after severe maternal morbidity.

Abstract

Pregnancy complications including severe maternal morbidity have been linked with an increased risk of cardiovascular disease, and provide opportunities to identify women who would benefit from prevention. Severe maternal morbidity comprises life-endangering complications around the time of pregnancy and delivery. Literature on the relationship between severe maternal morbidity and cardiovascular disease is increasing at a rapid pace. Studies have shown that severe preeclampsia or eclampsia and severe hemorrhage are associated with cardiovascular disease later in life. Proposed pathways include endothelial damage, hypercoagulability, and impaired cardiac function that are induced or exacerbated by severe pregnancy complications that elevate cardiovascular risks. However, less is known about other types of severe maternal morbidity that may influence the risk of cardiovascular disease. Other research gaps include a need to better understand the pathways and mechanisms linking severe maternal morbidity with cardiovascular disease, the potential for cardiovascular recovery after severe cardiovascular events during pregnancy, and disparities in the occurrence of cardiovascular disease after severe maternal morbidity.

Get Citation

Keywords

cardiovascular disease, heart disease, maternal near-miss, pregnancy complications, severe maternal morbidity

About this article
Title

Severe maternal morbidity and risk of cardiovascular disease: Recent advances

Journal

Kardiologia Polska (Polish Heart Journal)

Issue

Vol 80, No 6 (2022)

Article type

Review paper

Pages

638-643

Published online

2022-05-04

Page views

582

Article views/downloads

121

DOI

10.33963/KP.a2022.0119

Pubmed

35521721

Bibliographic record

Kardiol Pol 2022;80(6):638-643.

Keywords

cardiovascular disease
heart disease
maternal near-miss
pregnancy complications
severe maternal morbidity

Authors

Ugochinyere Vivian Ukah
Nathalie Auger

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