Vol 67, No 11 (2009)
Other
Published online: 2009-12-07
Case report
Pulmonary embolism as a first manifestation of synchronous occurrence of two neoplasms
DOI: 10.33963/v.kp.80315
Kardiol Pol 2009;67(11):1262-1266.
Abstract
A case of 67-year-old man with a first episode of acute, unprovoked venous thromboembolism (VTE). Screening for cancer revealed coexistence of two neoplasms: colon sigmoid cancer (operated on 6 weeks after pulmonary embolism onset), and multiple myeloma (treated successfully with thalidomide and dexamethasone). Low molecular weight heparin use as VTE treatment was followed by thromboprophylaxis for myeloma therapy. During a 30-month follow-up period, neither new thromboembolic complications nor cancer recurrence were observed. Overlapping different prothrombotic mechanisms of double malignancy might result in detection of both neoplasms at early stage.
Keywords: venous thromboembolismscreening for cancercolon cancermultiple myelomathalidomide