Vol 68, No 9 (2010)
Reviews
Published online: 2010-09-21

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Orthostatic hypotension and supine hypertension in primary autonomic failure. Pathophysiology, diagnosis and treatment

Tomasz Tykocki, Krystyna Guzek, Paweł Nauman
DOI: 10.33963/v.kp.79615
Kardiol Pol 2010;68(9):1057-1063.

Abstract

There are three diseases classified as primary autonomic failure (PAF), multiple system atrophy, Parkinson’s disease, pure autonomic failure. Compensatory mechanisms preventing from decrease in blood pressure are inefficient in PAF. Among half of the patients with PAF occur orthostatic hypotension (OH) and supine hypertension (SH), which are the cause of deterioration of life quality. The treatment is based on modification of lifestyle and pharmacotherapy. Drugs used in OH may exacerbate SH and vice versa.
Kardiol Pol 2010; 68, 9: 1057-1063

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Polish Heart Journal (Kardiologia Polska)