Vol 69, No 6 (2011)
Chorzy trudni typowi
Published online: 2011-06-15
Depression, its therapy and venous thromboembolism: three cases of pulmonary embolism
DOI: 10.33963/v.kp.79289
Kardiol Pol 2011;69(6):596-599.
Abstract
The associations between depression and coronary heart disease, especially via platelet hyperactivity, have been widely
described. The relationships between depression and venous thromboembolism are less clear. We present three cases of
pulmonary embolism (PE) in patients with previously diagnosed depression and discuss possible, depression-related prothrombotic
factors, including the impact of psychotropic drugs. A 69 year-old woman, treated with different antidepressants
and also antipsychotics, died two months after recurrent PE. Another woman, at the same age, on mirtazapine therapy,
developed segmental PE. In a 39 year-old man, taking paroxetine, severe PE required thrombolysis.
Kardiol Pol 2011; 69, 6: 596–599
Kardiol Pol 2011; 69, 6: 596–599
Keywords: venous thromboembolismpulmonary embolismdepressionpsychotropic drugs