Vol 69, Supp. III (2011)
Reviews
Published online: 2011-11-24
Conditioning the heart in cardiac surgery
DOI: 10.33963/v.kp.79154
Abstract
Cardiac surgery is associated with ischaemic and reperfusion injury to the myocardium. It seems natural to seek a possibility
of inducing the natural endoprotective mechanisms known as myocardial conditioning, including preconditioning, postconditioning,
and remote conditioning. Still, in spite of almost 20 years of research in the field, we are far from routine widespread
usage of these methods, with published reports describing quite various, and often contradictory results. Current
review summarises the trials of using the conditioning in cardiac surgical practice including pharmacological manipulations to
induce resistance to ischaemia-reperfusion.
Kardiol Pol 2011; 69, supl. III: 80–84
Kardiol Pol 2011; 69, supl. III: 80–84
Keywords: cardiac surgeryischaemia/reperfusionischaemic preconditioningischaemic postconditioningremote preconditioningpharmacological preconditioning