open access

Vol 69, No 2 (2018)
TROPICAL MILITARY MEDICINE Original articles
Published online: 2018-06-22
Submitted: 2018-05-18
Accepted: 2018-06-12
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Hepatitis E virus seroprevalence in Polish soldiers serving in harsh environmental conditions

Krzysztof Korzeniewski, Justyna Osińska, Jolanta Korsak, Monika Konior
DOI: 10.5603/IMH.2018.0020
·
Pubmed: 29939391
·
International Maritime Health 2018;69(2):137-141.

open access

Vol 69, No 2 (2018)
TROPICAL MILITARY MEDICINE Original articles
Published online: 2018-06-22
Submitted: 2018-05-18
Accepted: 2018-06-12

Abstract

Background: Hepatitis E virus (HEV) is an under-recognised aetiological factor of viral hepatitis; it is most
commonly transmitted via the oral-faecal route, but can also be transmitted by blood or blood products,
vertically from an infected mother to the foetus or by transplanted organs. The aim of the study was to
present the current seroprevalence of HEV among soldiers from the Polish Special Forces deployed on
military operations carried out in harsh environmental conditions.


Materials and methods: The research conducted between October and November 2016 involved 253 active
duty soldiers, 237 men and 16 women, aged 26–57, without clinical symptoms of infection, participants in
military operations in Asia and Africa. Accurate HEV diagnosis required the implementation of a two-phase
diagnostic protocol. During the first phase, immunoenzymatic ELISA method was used to detect specific
anti-HEV antibodies (IgM and IgG) in blood serum samples indicating contact with an infectious agent in
the past. During the second phase, serum samples obtained from subjects with positive or inconclusive
test results were tested again using confirmatory recomLine HEV IgM/IgG immunoassay.


Results: Immunoenzymatic assay found anti-HEV antibodies (IgM and/or IgG) in blood serum samples
obtained from 18 soldiers. Confirmatory tests were carried out among soldiers tested positive with ELISA
or those with inconclusive test results; the confirmatory tests showed anti-HEV antibodies (IgM and/or IgG)
in 16 of the studied soldiers, i.e. 6.3% of the study group.


Conclusions: The occurrence of HEV infections in Polish soldiers justifies the need for the introduction of
screening tests for HEV in the military environment, especially among blood donors and in cases of whole
blood or blood products transfusion.

Abstract

Background: Hepatitis E virus (HEV) is an under-recognised aetiological factor of viral hepatitis; it is most
commonly transmitted via the oral-faecal route, but can also be transmitted by blood or blood products,
vertically from an infected mother to the foetus or by transplanted organs. The aim of the study was to
present the current seroprevalence of HEV among soldiers from the Polish Special Forces deployed on
military operations carried out in harsh environmental conditions.


Materials and methods: The research conducted between October and November 2016 involved 253 active
duty soldiers, 237 men and 16 women, aged 26–57, without clinical symptoms of infection, participants in
military operations in Asia and Africa. Accurate HEV diagnosis required the implementation of a two-phase
diagnostic protocol. During the first phase, immunoenzymatic ELISA method was used to detect specific
anti-HEV antibodies (IgM and IgG) in blood serum samples indicating contact with an infectious agent in
the past. During the second phase, serum samples obtained from subjects with positive or inconclusive
test results were tested again using confirmatory recomLine HEV IgM/IgG immunoassay.


Results: Immunoenzymatic assay found anti-HEV antibodies (IgM and/or IgG) in blood serum samples
obtained from 18 soldiers. Confirmatory tests were carried out among soldiers tested positive with ELISA
or those with inconclusive test results; the confirmatory tests showed anti-HEV antibodies (IgM and/or IgG)
in 16 of the studied soldiers, i.e. 6.3% of the study group.


Conclusions: The occurrence of HEV infections in Polish soldiers justifies the need for the introduction of
screening tests for HEV in the military environment, especially among blood donors and in cases of whole
blood or blood products transfusion.

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Keywords

hepatitis E virus (HEV), seroprevalence, Polish soldiers

About this article
Title

Hepatitis E virus seroprevalence in Polish soldiers serving in harsh environmental conditions

Journal

International Maritime Health

Issue

Vol 69, No 2 (2018)

Pages

137-141

Published online

2018-06-22

DOI

10.5603/IMH.2018.0020

Pubmed

29939391

Bibliographic record

International Maritime Health 2018;69(2):137-141.

Keywords

hepatitis E virus (HEV)
seroprevalence
Polish soldiers

Authors

Krzysztof Korzeniewski
Justyna Osińska
Jolanta Korsak
Monika Konior

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