Vol 10, No 4 (2019)
Letter to the Editor
Published online: 2020-04-23

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Clinically diverse sickle cell disease influenced by genetic factors

Henu Kumar Verma1
Hematologia 2019;10(4):197-198.


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  2. Nongbri SR, Verma HK, Lakkakula BV, et al. Presence of atypical beta globin (HBB) gene cluster haplotypes in sickle cell anemia patients of India. Rev Bras Hematol Hemoter. 2017; 39(2): 180–182.
  3. Nishank SS, Singh MP, Yadav R, et al. Endothelial nitric oxide synthase gene polymorphism is associated with sickle cell disease patients in India. J Hum Genet. 2013; 58(12): 775–779.
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  5. Verma H, Mishra H, Khodiar PK, et al. NOS3 27-bp and IL4 70-bp VNTR Polymorphisms Do Not Contribute to the Risk of Sickle Cell Crisis. Turk J Haematol. 2016; 33(4): 365–366.
  6. Bhanushali AA, Patra PK, Nair D, et al. Genetic variant in the BCL11A (rs1427407), but not HBS1-MYB (rs6934903) loci associate with fetal hemoglobin levels in Indian sickle cell disease patients. Blood Cells Mol Dis. 2015; 54(1): 4–8.
  7. Rumaney MB, Ngo Bitoungui VJ, Vorster AA, et al. The co-inheritance of alpha-thalassemia and sickle cell anemia is associated with better hematological indices and lower consultations rate in Cameroonian patients and could improve their survival. PLoS One. 2014; 9(6): e100516.

Hematology in Clinical Practice