open access

Vol 2, No 1 (2011)
Review paper
Published online: 2011-03-24
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Deferasirox (Exjade®) as iron chelator in children

Michał Matysiak
Hematologia 2011;2(1):83-87.

open access

Vol 2, No 1 (2011)
REVIEW ARTICLES
Published online: 2011-03-24

Abstract

Patients receiving recurrent blood transfusion as supportive therapy of chronic anemia in the course of myelodysplastic syndromes, thalassemia and sickle-cell disease, are at risk of iron accumulation. The clinical consequences of iron overload can be fatal. Therefore, the use of a chelating agent is required to promote excretion of iron. At the present time, new iron chelators that can be given orally are available. Deferasirox is a once-daily oral therapy for treating transfusional iron overload, which improves patient compliance and quality of his life.
Hematologia 2011; 2, 1: 83–87

Abstract

Patients receiving recurrent blood transfusion as supportive therapy of chronic anemia in the course of myelodysplastic syndromes, thalassemia and sickle-cell disease, are at risk of iron accumulation. The clinical consequences of iron overload can be fatal. Therefore, the use of a chelating agent is required to promote excretion of iron. At the present time, new iron chelators that can be given orally are available. Deferasirox is a once-daily oral therapy for treating transfusional iron overload, which improves patient compliance and quality of his life.
Hematologia 2011; 2, 1: 83–87
Get Citation

Keywords

chelation therapy; iron overload; deferasirox; deferoxamine

About this article
Title

Deferasirox (Exjade®) as iron chelator in children

Journal

Hematology in Clinical Practice

Issue

Vol 2, No 1 (2011)

Article type

Review paper

Pages

83-87

Published online

2011-03-24

Bibliographic record

Hematologia 2011;2(1):83-87.

Keywords

chelation therapy
iron overload
deferasirox
deferoxamine

Authors

Michał Matysiak

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