dostęp otwarty

Tom 8, Nr 3 (2017)
PRACE POGLĄDOWE
Opublikowany online: 2017-11-23
Pobierz cytowanie

Rozpoznawanie i leczenie chorych na nowotwory z dojrzałych komórek T i NK

Krzysztof Warzocha, Bartosz Puła
DOI: 10.5603/Hem.2017.0022
·
Hematologia 2017;8(3):177-196.

dostęp otwarty

Tom 8, Nr 3 (2017)
PRACE POGLĄDOWE
Opublikowany online: 2017-11-23

Streszczenie

Nowotwory z dojrzałych komórek T i NK stanowią heterogenną grupę chorób wywodzących się z układu chłonnego. Do tej kategorii zalicza się 10–15% chłoniaków. Charakteryzuje je zróżnico¬wany obraz kliniczny i patomorfologiczny, częste lokalizacje pozawęzłowe oraz niekorzystne roko¬wanie. Ich stosunkowo rzadkie występowanie, duża heterogenność oraz brak randomizowanych badań klinicznych utrudniają opracowanie ujednoliconych standarów terapeutycznych. Niemniej chemioterapia oraz przeszczepianie krwiotwórczych komórek macierzystych zdają się być skuteczną metodą w leczeniu pierwszej linii oraz przypadków opornych i nawrotowych. W niniejszym artykule omówiono wytyczne diagnostyki i leczenia tej zróżnicowanej grupy nowotworów.

Streszczenie

Nowotwory z dojrzałych komórek T i NK stanowią heterogenną grupę chorób wywodzących się z układu chłonnego. Do tej kategorii zalicza się 10–15% chłoniaków. Charakteryzuje je zróżnico¬wany obraz kliniczny i patomorfologiczny, częste lokalizacje pozawęzłowe oraz niekorzystne roko¬wanie. Ich stosunkowo rzadkie występowanie, duża heterogenność oraz brak randomizowanych badań klinicznych utrudniają opracowanie ujednoliconych standarów terapeutycznych. Niemniej chemioterapia oraz przeszczepianie krwiotwórczych komórek macierzystych zdają się być skuteczną metodą w leczeniu pierwszej linii oraz przypadków opornych i nawrotowych. W niniejszym artykule omówiono wytyczne diagnostyki i leczenia tej zróżnicowanej grupy nowotworów.
Pobierz cytowanie

Słowa kluczowe

nowotwory z dojrzałych limfocytów T i NK, chemioterapia, przeszczepianie krwiotwórczych komórek macierzystych, rokowanie, diagnostyka

Informacje o artykule
Tytuł

Rozpoznawanie i leczenie chorych na nowotwory z dojrzałych komórek T i NK

Czasopismo

Hematologia

Numer

Tom 8, Nr 3 (2017)

Strony

177-196

Data publikacji on-line

2017-11-23

DOI

10.5603/Hem.2017.0022

Rekord bibliograficzny

Hematologia 2017;8(3):177-196.

Słowa kluczowe

nowotwory z dojrzałych limfocytów T i NK
chemioterapia
przeszczepianie krwiotwórczych komórek macierzystych
rokowanie
diagnostyka

Autorzy

Krzysztof Warzocha
Bartosz Puła

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