open access

Vol 88, No 1 (2017)
Research paper
Published online: 2017-01-31
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The incidence of cervical intraepithelial neoplasia in a population of pregnant women with an abnormal cytology

Dominik Pruski, Blanka Malkowska-Walczak, Aleksandra Paluszkiewicz, Witold Kędzia
·
Pubmed: 28157250
·
Ginekol Pol 2017;88(1):20-23.

open access

Vol 88, No 1 (2017)
ORIGINAL PAPERS Obstetrics
Published online: 2017-01-31

Abstract

Objectives: To assess the incidence of cervical intraepithelial neoplasia — SIL and cervical cancer in a population of pregnant women with an abnormal cytology.

Material and methods: In pregnant women with abnormal cytology results according to The Bethesda System, a verifying diagnostics was carried out, including colposcopy and cervical biopsy.

Results: The most common histological and oncologic diagnosis in the whole study group of pregnant women were HGSIL changes, covering cervical intraepithelial neoplasia of medium and high grade — CIN 2 and CIN 3.

Conclusions: HGSIL changes are the most common oncological pathology in a population of pregnant women with an abnormal cytology. Precise risk identification of HGSIL changes with the use of molecular tests can significantly reduce the number of surgical procedures in a population of pregnant patients with a cytological diagnosis of ASCUS and LSIL.

Abstract

Objectives: To assess the incidence of cervical intraepithelial neoplasia — SIL and cervical cancer in a population of pregnant women with an abnormal cytology.

Material and methods: In pregnant women with abnormal cytology results according to The Bethesda System, a verifying diagnostics was carried out, including colposcopy and cervical biopsy.

Results: The most common histological and oncologic diagnosis in the whole study group of pregnant women were HGSIL changes, covering cervical intraepithelial neoplasia of medium and high grade — CIN 2 and CIN 3.

Conclusions: HGSIL changes are the most common oncological pathology in a population of pregnant women with an abnormal cytology. Precise risk identification of HGSIL changes with the use of molecular tests can significantly reduce the number of surgical procedures in a population of pregnant patients with a cytological diagnosis of ASCUS and LSIL.

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Keywords

cervical intraepithelial neoplasia, pregnancy, HGSIL

Supp./Additional Files (4)
Percentage proportions of all histopathological diagnoses in the population of pregnant patients aged from 18 to 47 (n = 184).
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The number of individual abnormal cytologic diagnoses in the general population of pregnant patients.
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Percantage proportion of individual abnormal cytological diagnoses in pregnant patients with histopathologic diagnosis of HGSIL and adenocarcinoma, LGSIL or negative for intraepithelial lesion or malignancy - NILM.
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52KB
The incidence of histopathologic diagnoses in certain age groups.
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63KB
About this article
Title

The incidence of cervical intraepithelial neoplasia in a population of pregnant women with an abnormal cytology

Journal

Ginekologia Polska

Issue

Vol 88, No 1 (2017)

Article type

Research paper

Pages

20-23

Published online

2017-01-31

Page views

1883

Article views/downloads

2375

DOI

10.5603/GP.a2017.0004

Pubmed

28157250

Bibliographic record

Ginekol Pol 2017;88(1):20-23.

Keywords

cervical intraepithelial neoplasia
pregnancy
HGSIL

Authors

Dominik Pruski
Blanka Malkowska-Walczak
Aleksandra Paluszkiewicz
Witold Kędzia

References (14)
  1. Insinga RP, Glass AG, Rush BB. Diagnoses and outcomes in cervical cancer screening: a population-based study. Am. J. Obstet. Gynecol. 2004; 191(1): 105–113.
  2. Douvier S, Filipuzzi L, Sagot P. [Management of cervical intra-epithelial neoplasm during pregnancy]. Gynecol Obstet Fertil. 2003; 31(10): 851–855.
  3. Morimura Y, Fujimori K, Soeda S, et al. Cervical cytology during pregnancy--comparison with non-pregnant women and management of pregnant women with abnormal cytology. Fukushima J Med Sci. 2002; 48(1): 27–37.
  4. Wojciechowska U, Didkowska J. Nowotwory w Polsce w 2012 roku. Nowotwory. Journal of Oncology. 2013; 63(3): 197–216.
  5. Wojciechowska U, Didkowska J. Zachorowania i zgony na nowotwory złośliwe w Polsce, Krajowy Rejestr Nowotworów, Centrum Onkologii – Instytut im. M. Skłodowskiej-Curie, http://onkologia.org. pl/raporty z dnia 25. ; 11: 2014.
  6. Pisharodi LR, Jovanoska S. Spectrum of cytologic changes in pregnancy. A review of 100 abnormal cervicovaginal smears, with emphasis on diagnostic pitfalls. Acta Cytol. 1995; 39(5): 905–908.
  7. Michael CW, Esfahani FM. Pregnancy-related changes: a retrospective review of 278 cervical smears. Diagn. Cytopathol. 1997; 17(2): 99–107, doi: 10.1002/(sici)1097-0339(199708)17:2<99::aid-dc4>3.3.co;2-6.
  8. Xavier-Júnior JC, Dufloth RM, do Vale DB, et al. High-grade squamous intraepithelial lesions in pregnant and non-pregnant women. Eur. J. Obstet. Gynecol. Reprod. Biol. 2014; 175: 103–106.
  9. Al-Halal H, Kezouh A, Abenhaim H. Incidence and obstetrical outcomes of cervical intraepithelial neoplasia and cervical cancer in pregnancy. Archives of Gynecology and Obstetrics. 2012; 287(2): 245–250.
  10. Al-Halal H, Kezouh A, Abenhaim HA. Incidence and obstetrical outcomes of cervical intraepithelial neoplasia and cervical cancer in pregnancy: a population-based study on 8.8 million births. Arch. Gynecol. Obstet. 2013; 287(2): 245–250.
  11. Ahdoot D, Van Nostrand KM, Nguyen NJ, et al. The effect of route of delivery on regression of abnormal cervical cytologic findings in the postpartum period. Am. J. Obstet. Gynecol. 1998; 178(6): 1116–1120.
  12. Paraskevaidis E, Koliopoulos G, Kalantaridou S, et al. Management and evolution of cervical intraepithelial neoplasia during pregnancy and postpartum. Eur. J. Obstet. Gynecol. Reprod. Biol. 2002; 104(1): 67–69.
  13. Reid JL, Wright TC, Stoler MH, et al. Human papillomavirus oncogenic mRNA testing for cervical cancer screening: baseline and longitudinal results from the CLEAR study. Am. J. Clin. Pathol. 2015; 144(3): 473–483.
  14. Andersson E, Kärrberg C, Rådberg T, et al. Type-specific human papillomavirus E6/E7 mRNA detection by real-time PCR improves identification of cervical neoplasia. J. Clin. Microbiol. 2011; 49(11): 3794–3799.

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