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Does body mass index affect anti-mullerian hormone levels in girls and adolescents?
Affiliations- Chair and Department of Gynecology, Obstetrics and Oncological Gynecology, Medical University of Silesia in Katowice, Poland
- Zakład Diagnostyki Laboratoryjnej Górnośląskiego Centrum Zdrowia Dziecka w Katowicach
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Abstract
Anti-mullerian hormone (AMH) is a dimeric glycoprotein which belongs to the transforming growth factor-beta superfamily. In women, it is produced by granulosa cells in pre-antral and small antral follicles. In recent years, there has been a continuous increase in obesity among children and adolescents. There are few studies that present AMH concentrations in premenarcheal and early postmenarcheal girls. The purpose of this work is to assess whether AMH levels were associated with body mass index (BMI) in adolescent girls before and after menarche. The study was performed at the Pediatric Endocrinology Department and Outpatient Clinic at Upper Silesian Child Health Center. 82 girls were enrolled to the study. Body mass index seems not to affect the AMH levels in adolescents, however a special attention must be given when interpreting AMH levels in girls with irregular menstrual cycles and observed for PCOS.
Abstract
Anti-mullerian hormone (AMH) is a dimeric glycoprotein which belongs to the transforming growth factor-beta superfamily. In women, it is produced by granulosa cells in pre-antral and small antral follicles. In recent years, there has been a continuous increase in obesity among children and adolescents. There are few studies that present AMH concentrations in premenarcheal and early postmenarcheal girls. The purpose of this work is to assess whether AMH levels were associated with body mass index (BMI) in adolescent girls before and after menarche. The study was performed at the Pediatric Endocrinology Department and Outpatient Clinic at Upper Silesian Child Health Center. 82 girls were enrolled to the study. Body mass index seems not to affect the AMH levels in adolescents, however a special attention must be given when interpreting AMH levels in girls with irregular menstrual cycles and observed for PCOS.
Keywords
AMH; BMI; obesity; adolescents; pediatric endocrinology
About this articleTitle
Does body mass index affect anti-mullerian hormone levels in girls and adolescents?
Journal
Issue
Article type
Research paper
Published online
2023-02-10
Page views
102
Article views/downloads
63
DOI
10.5603/GP.a2023.0013
Pubmed
Keywords
AMH
BMI
obesity
adolescents
pediatric endocrinology
Authors
Iwona Czech
Mirosław Partyka
Agnieszka Drosdzol-Cop
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