open access

Vol 94, No 4 (2023)
Research paper
Published online: 2023-03-16
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CoronaVac vaccine does not affect ovarian reserve

Ayşe Rabia Şenkaya1, Zafer Çil2, Ömür Keskin1, Mehmet Emin Güneş1, Deniz Can Öztekin1
·
Pubmed: 36929802
·
Ginekol Pol 2023;94(4):298-302.
Affiliations
  1. Gynecology and Obstetrics Clinic, İzmir Bakırçay University Çiğli Training and Research Hospital, Turkey
  2. Biochemistry, İzmir Bakırçay University Çiğli Training and Research Hospital, Turkey

open access

Vol 94, No 4 (2023)
ORIGINAL PAPERS Gynecology
Published online: 2023-03-16

Abstract

Objectives: In this study, our aim is to investigate the effect of CoronaVac vaccine on ovarian reserve in female patients followed up for infertility.
Material and methods: Our study is a retrospective study. Forty-six infertile patients who received two doses of CoronaVac vaccine one month apart and had not had a previous Covid 19 infection were included in the study. Anti-müllerian hormone (AMH) and folliculometry of 46 patients one month before CoronaVac vaccine and one month after the second dose of vaccine were compared.
Results: There was no statistically significant difference in the change of AMH level and follicle number before and after vaccination (respectively p = 0.366; 0.610).
Conclusions: Considering that having a COVID-19 infection has a negative effect on female fertility and causing ovarian damage in recent studies, vaccination is a rational and cost-effective approach to protect ovarian reserve. Knowing that the vaccine does not have a negative effect on fertility may increase the application of the vaccine in women of reproductive age.

Abstract

Objectives: In this study, our aim is to investigate the effect of CoronaVac vaccine on ovarian reserve in female patients followed up for infertility.
Material and methods: Our study is a retrospective study. Forty-six infertile patients who received two doses of CoronaVac vaccine one month apart and had not had a previous Covid 19 infection were included in the study. Anti-müllerian hormone (AMH) and folliculometry of 46 patients one month before CoronaVac vaccine and one month after the second dose of vaccine were compared.
Results: There was no statistically significant difference in the change of AMH level and follicle number before and after vaccination (respectively p = 0.366; 0.610).
Conclusions: Considering that having a COVID-19 infection has a negative effect on female fertility and causing ovarian damage in recent studies, vaccination is a rational and cost-effective approach to protect ovarian reserve. Knowing that the vaccine does not have a negative effect on fertility may increase the application of the vaccine in women of reproductive age.

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Keywords

anti mullerian hormone; CoronaVac; infertility; ovarian follicle; vaccination

About this article
Title

CoronaVac vaccine does not affect ovarian reserve

Journal

Ginekologia Polska

Issue

Vol 94, No 4 (2023)

Article type

Research paper

Pages

298-302

Published online

2023-03-16

Page views

1987

Article views/downloads

297

DOI

10.5603/GP.a2023.0025

Pubmed

36929802

Bibliographic record

Ginekol Pol 2023;94(4):298-302.

Keywords

anti mullerian hormone
CoronaVac
infertility
ovarian follicle
vaccination

Authors

Ayşe Rabia Şenkaya
Zafer Çil
Ömür Keskin
Mehmet Emin Güneş
Deniz Can Öztekin

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