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A rare case of hemimegalencephaly diagnosed prenatally
, 2, 1
Affiliations- Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Cracow, Poland
- Department of Diagnostic Imaging Institute of Mother and Child, Warsaw, Poland
open access
Abstract
Hemimegalencephaly (HME), or unilateral megalencephaly, is a rare congenital brain malformation defined as
overgrowth of one cerebral hemisphere or part of it resulting from abnormal cortical development and neuronal
migration. However, cortical developmental abnormalities are rarely diagnosed prenatally. This is the reason for our
study, in which we describe and compare ultrasound and MRI findings in a fetus with HME.
Abstract
Hemimegalencephaly (HME), or unilateral megalencephaly, is a rare congenital brain malformation defined as
overgrowth of one cerebral hemisphere or part of it resulting from abnormal cortical development and neuronal
migration. However, cortical developmental abnormalities are rarely diagnosed prenatally. This is the reason for our
study, in which we describe and compare ultrasound and MRI findings in a fetus with HME.
Keywords
fetus; hemimegalencephaly; central nervous system; ultrasound
About this articleTitle
A rare case of hemimegalencephaly diagnosed prenatally
Journal
Issue
Article type
Clinical vignette
Pages
677-678
Published online
2022-05-25
Page views
4440
Article views/downloads
667
DOI
Pubmed
Bibliographic record
Ginekol Pol 2022;93(8):677-678.
Keywords
fetus
hemimegalencephaly
central nervous system
ultrasound
Authors
Anna Wojtowicz
Agnieszka Duczkowska
Hubert Huras
References (5)- Flores-Sarnat L. Hemimegalencephaly: part 1. Genetic, clinical, and imaging aspects. J Child Neurol. 2002; 17(5): 373–84; discussion 384.
- Manoranjan B, Provias JP. Hemimegalencephaly: a fetal case with neuropathological confirmation and review of the literature. Acta Neuropathol. 2010; 120(1): 117–130.
- Alvarez RM, García-Díaz L, Márquez J, et al. Hemimegalencephaly: prenatal diagnosis and outcome. Fetal Diagn Ther. 2011; 30(3): 234–238.
- Romero XC, Molina FS, Pastor E, et al. Hemimegalencephaly: 2D, 3D Ultrasound and MRI Correlation. Fetal Diagn Ther. 2011; 29(3): 257–260.
- Senapati G, Levine D. Prenatal-postnatal correlations of brain abnormalities: how lesions and diagnoses change over time. J Pediatr Neuroradiol. 2012; 1(3): 171–184.
