open access

Vol 94, No 2 (2023)
Research paper
Published online: 2022-05-26
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Influence of gestational diabetes in twin pregnancy on the condition of newborns and early neonatal complications

Bartlomiej Myszkowski1, Agata Stawska1, Malgorzata Glogiewicz1, Marta I. Sekielska-Domanowska1, Sawa Wisniewska-Cymbaluk1, Rafal Adamczak1, Jaroslaw Lach1, Wojciech Cnota2, Mariusz Dubiel1
·
Pubmed: 35894496
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Ginekol Pol 2023;94(2):129-134.
Affiliations
  1. Department of Obstetrics, Gynecology and Gynecological Oncology, Faculty of Medicine, Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland
  2. Clinical Department of Perinatology, Gynaecology and Obstetrics in Ruda Slaska, Medical University of Silesia, Ruda Slaska, Poland

open access

Vol 94, No 2 (2023)
ORIGINAL PAPERS Obstetrics
Published online: 2022-05-26

Abstract

Objectives: Diabetes mellitus is the most common metabolic complication in pregnancy and increasing worldwide. In Europe, it occurs in 3–5% of pregnant women. The rate of twin pregnancy has been increased similarly to gestational diabetes mellitus (GDM). Twin pregnancy is associated with a higher complication rate compared to singleton pregnancy. The growing prevalence of GDM and twin pregnancy has given rise to their increasing concurrent presentation. Material and methods: The retrospective analysis included 212 twin-pregnant patients. The analysis excluded cases of miscarriage and early fetal death in the first trimester of pregnancy. The influence of GDM on the condition of newborns and mothers after delivery was analyzed. For statistical analysis R 3.6.2 software was used. Results: No statistically significant relationship between GDM and Non-GDM group and periparturient complications was found. Birth weight was significantly higher in the GDM G2 group. Apgar Score was the lowest in the GDM G1 group. In the group of larger newborns of the GDMG1 group respiratory distress syndrome (RDS) , a higher incidence of second-degree intracranial bleeding and grade II of preterm retinopathy were observed. There was no statistically significant relationship between GDM G1, GDM G2 and other neonatal complications. Conclusions: In summary, our results indicate that GDM in twin pregnancy does not increase the risk of cesarean section but increases some neonatal complications. In conclusion women with twin pregnancies complicated by GDM require specialist care during pregnancy and childbirth should take place in a third-level reference center.

Abstract

Objectives: Diabetes mellitus is the most common metabolic complication in pregnancy and increasing worldwide. In Europe, it occurs in 3–5% of pregnant women. The rate of twin pregnancy has been increased similarly to gestational diabetes mellitus (GDM). Twin pregnancy is associated with a higher complication rate compared to singleton pregnancy. The growing prevalence of GDM and twin pregnancy has given rise to their increasing concurrent presentation. Material and methods: The retrospective analysis included 212 twin-pregnant patients. The analysis excluded cases of miscarriage and early fetal death in the first trimester of pregnancy. The influence of GDM on the condition of newborns and mothers after delivery was analyzed. For statistical analysis R 3.6.2 software was used. Results: No statistically significant relationship between GDM and Non-GDM group and periparturient complications was found. Birth weight was significantly higher in the GDM G2 group. Apgar Score was the lowest in the GDM G1 group. In the group of larger newborns of the GDMG1 group respiratory distress syndrome (RDS) , a higher incidence of second-degree intracranial bleeding and grade II of preterm retinopathy were observed. There was no statistically significant relationship between GDM G1, GDM G2 and other neonatal complications. Conclusions: In summary, our results indicate that GDM in twin pregnancy does not increase the risk of cesarean section but increases some neonatal complications. In conclusion women with twin pregnancies complicated by GDM require specialist care during pregnancy and childbirth should take place in a third-level reference center.

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Keywords

twins; GDM; newborn; neonatal; complications

About this article
Title

Influence of gestational diabetes in twin pregnancy on the condition of newborns and early neonatal complications

Journal

Ginekologia Polska

Issue

Vol 94, No 2 (2023)

Article type

Research paper

Pages

129-134

Published online

2022-05-26

Page views

2981

Article views/downloads

676

DOI

10.5603/GP.a2022.0037

Pubmed

35894496

Bibliographic record

Ginekol Pol 2023;94(2):129-134.

Keywords

twins
GDM
newborn
neonatal
complications

Authors

Bartlomiej Myszkowski
Agata Stawska
Malgorzata Glogiewicz
Marta I. Sekielska-Domanowska
Sawa Wisniewska-Cymbaluk
Rafal Adamczak
Jaroslaw Lach
Wojciech Cnota
Mariusz Dubiel

References (14)
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  2. Kim Y, Hong SY, Kim SY, et al. Obstetric and neonatal outcomes of gestational diabetes mellitus in twin pregnancies according to changes in its diagnostic criteria from National Diabetes Data Group criteria to Carpenter and Coustan criteria: a retrospective cohort study. BMC Pregnancy Childbirth. 2022; 22(1): 9.
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  8. Hung TH, Hsieh TT, Shaw SW, et al. Risk factors and adverse maternal and perinatal outcomes for women with dichorionic twin pregnancies complicated by gestational diabetes mellitus: A retrospective cross-sectional study. J Diabetes Investig. 2021; 12(6): 1083–1091.
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