Vol 94, No 2 (2023)
Research paper
Published online: 2022-05-26

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Influence of gestational diabetes in twin pregnancy on the condition of newborns and early neonatal complications

Bartlomiej Myszkowski1, Agata Stawska1, Malgorzata Glogiewicz1, Marta I. Sekielska-Domanowska1, Sawa Wisniewska-Cymbaluk1, Rafal Adamczak1, Jaroslaw Lach1, Wojciech Cnota2, Mariusz Dubiel1
Pubmed: 35894496
Ginekol Pol 2023;94(2):129-134.

Abstract

Objectives: Diabetes mellitus is the most common metabolic complication in pregnancy and increasing worldwide. In Europe, it occurs in 3–5% of pregnant women. The rate of twin pregnancy has been increased similarly to gestational diabetes mellitus (GDM). Twin pregnancy is associated with a higher complication rate compared to singleton pregnancy. The growing prevalence of GDM and twin pregnancy has given rise to their increasing concurrent presentation. Material and methods: The retrospective analysis included 212 twin-pregnant patients. The analysis excluded cases of miscarriage and early fetal death in the first trimester of pregnancy. The influence of GDM on the condition of newborns and mothers after delivery was analyzed. For statistical analysis R 3.6.2 software was used. Results: No statistically significant relationship between GDM and Non-GDM group and periparturient complications was found. Birth weight was significantly higher in the GDM G2 group. Apgar Score was the lowest in the GDM G1 group. In the group of larger newborns of the GDMG1 group respiratory distress syndrome (RDS) , a higher incidence of second-degree intracranial bleeding and grade II of preterm retinopathy were observed. There was no statistically significant relationship between GDM G1, GDM G2 and other neonatal complications. Conclusions: In summary, our results indicate that GDM in twin pregnancy does not increase the risk of cesarean section but increases some neonatal complications. In conclusion women with twin pregnancies complicated by GDM require specialist care during pregnancy and childbirth should take place in a third-level reference center.

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