Vol 93, No 11 (2022)
Research paper
Published online: 2022-06-28

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Meta-analysis for the evaluation of perioperative enhanced recovery after gynaecological surgery

Xiaofang  Wu1, Lingling Liu1, Fang  Zhou1
Pubmed: 36621969
Ginekol Pol 2022;93(11):896-903.

Abstract

Objectives: To systematically evaluate the effectiveness and safety of enhanced recovery after surgery (ERAS) in gynaecological surgery and provide a scientific basis for its clinical promotion and application in the Chinese population.

Material and methods: Systematic retrieval from CNKI, Wanfang, VIP database and other Chinese literature databases. Studies on ERAS application with a randomised controlled trial in gynaecological surgery were included in the present report. Outcome indicators: hospitalisation time, postoperative ambulation time, postoperative feeding time, postoperative exhaust time, postoperative defecation time, operation time, postoperative blood loss, postoperative morbidity, patient satisfaction, hospitalisation expenses, etc. The meta-analysis was performed using the Revman 5.3 software.

Results: A total of 24 studies were included in the analysis. The results showed that, compared with the traditional
group, the ERAS group had a lower hospitalisation time (SMD = −1.67, 95% CI = −2.03 ~ −1.30, p < 0.0001), postoperative ambulation time (SMD = −4.16, 95% CI = −5.12 ~ −3.20, p < 0.0001), postoperative feeding time (SMD = −7.36, 95% CI = −9.67 ~ −5.05, p < 0.0001), postoperative exhaust time (SMD = −2.59, 95% CI = −3.15 ~ −2.03, p < 0.0001), postoperative defecation time (SMD = −2.23, 95% CI = −2.88 ~ −1.57, p < 0.0001), postoperative morbidity (OR = 0.22, 95% CI = 0.15 ~ 0.31, p < 0.0001) and hospitalisation expenses (SMD = −0.53, 95% CI = −0.78 ~ −0.28, p < 0.0001). The patient satisfaction was significantly improved (odds ratio = 8.11, 95% CI = 4.96 ~ 13.24, p < 0.0001), and there were no significant differences in intraoperative blood loss and operation time between the two groups.

Conclusions: The application of the ERAS protocol in gynaecological surgery significantly improves the effectiveness
and safety of the procedure. Thus, it can be promoted and applied in clinical practice in China.

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