Vol 93, No 11 (2022)
Research paper
Published online: 2021-10-07

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Epidural anaesthesia and myomectomy-associated blood loss — a prospective randomised controlled study

Mohamed Farghali1, Abdelrady S. Ibrahim2, Waleed S. Farrag2
Pubmed: 35072219
Ginekol Pol 2022;93(11):861-866.


Objectives: The management of anaesthesia for patients with large myomas is particularly important due to disruption
of hemodynamic as a result of massive haemorrhage, the prolonged duration of surgery and requirement for additional
interventions. This study evaluated the effect of anaesthetic technique on blood loss in patients undergoing myomectomy
due to large fibroid uterus.

Material and methods: A total of 156 patients that underwent myomectomy were randomized into two equal groups
according to the type of anaesthesia: Epidural anaesthesia group and General anaesthesia group. The volume of blood
loss and blood products transfusion was reviewed for each patient.

Results: The intraoperative blood loss and need for blood transfusion were significantly higher in general anaesthesia
group (p < 0.001). The mean hematocrit change was 2.5 ± 1.5 vs 3.7 ± 2.9 % (p = 0.001) for both groups.

Conclusions: In the myomectomy planning of women with a large fibroid uterus, the team of gynecologists and anaesthesiologists should take care to choose the most optimal technique for anaesthesia.

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