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open access

Vol 94, No 4 (2023)
Research paper
Published online: 2021-12-17
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Platelet to lymphocyte and neutrophil to lymphocyte ratios in endometrial pathologies

Orkun Ilgen1, Sefa Kurt1, Resmiye Irmak Yuzuguldu2, Onur Ada1, Alper Mankan1
DOI: 10.5603/GP.a2021.0141
·
Pubmed: 35072230
·
Ginekol Pol 2023;94(4):269-274.
Affiliations
  1. Department of Obstetrics and Gynecology, 9 Eylul University School of Medicine, Izmir, Turkey
  2. Department of Obstetrics and Gynecology, Dokuz Eylul University, Medical Faculty, Turkey

open access

Vol 94, No 4 (2023)
ORIGINAL PAPERS Gynecology
Published online: 2021-12-17

Abstract

Objectives: Aim of this study was to evaluate the relationship between platelet to lymphocyte ratio (PLR), neutrophil to lymphocyte ratio (NLR), and endometrial pathologies.
Material and methods: The database of our institution was reviewed. Cases with endometrial pathology including endometrial cancer (EC), endometrial hyperplasia with atypia and without atypia, normal endometrial findings, between January 2015 to January 2020, were collected. Their CBC results and clinicopathologic data were determined. The relation between the platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), and endometrial pathologies was evaluated.
Results: NLR was significantly higher in patients with endometrial cancer compared to other endometrial pathologies including endometrial hyperplasia with and without atypia and patients with normal endometrial findings. NLR cut-off value was determined 3.55 to discriminate cancer among other endometrial pathologies. PLR had not a significant difference between the endometrial pathologies.
Conclusion: NLR seems to be an effective and simple marker to discriminate endometrial cancer among endometrial pathologies by contrast with PLR.

Abstract

Objectives: Aim of this study was to evaluate the relationship between platelet to lymphocyte ratio (PLR), neutrophil to lymphocyte ratio (NLR), and endometrial pathologies.
Material and methods: The database of our institution was reviewed. Cases with endometrial pathology including endometrial cancer (EC), endometrial hyperplasia with atypia and without atypia, normal endometrial findings, between January 2015 to January 2020, were collected. Their CBC results and clinicopathologic data were determined. The relation between the platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), and endometrial pathologies was evaluated.
Results: NLR was significantly higher in patients with endometrial cancer compared to other endometrial pathologies including endometrial hyperplasia with and without atypia and patients with normal endometrial findings. NLR cut-off value was determined 3.55 to discriminate cancer among other endometrial pathologies. PLR had not a significant difference between the endometrial pathologies.
Conclusion: NLR seems to be an effective and simple marker to discriminate endometrial cancer among endometrial pathologies by contrast with PLR.

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Keywords

neutrophil to lymphocyte ratio; platelet to lymphocyte ratio; endometrial cancer; endometrial pathologies

About this article
Title

Platelet to lymphocyte and neutrophil to lymphocyte ratios in endometrial pathologies

Journal

Ginekologia Polska

Issue

Vol 94, No 4 (2023)

Article type

Research paper

Pages

269-274

Published online

2021-12-17

Page views

2670

Article views/downloads

786

DOI

10.5603/GP.a2021.0141

Pubmed

35072230

Bibliographic record

Ginekol Pol 2023;94(4):269-274.

Keywords

neutrophil to lymphocyte ratio
platelet to lymphocyte ratio
endometrial cancer
endometrial pathologies

Authors

Orkun Ilgen
Sefa Kurt
Resmiye Irmak Yuzuguldu
Onur Ada
Alper Mankan

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