open access

Vol 92, No 9 (2021)
Research paper
Published online: 2021-04-08
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Predictors of poor neonatal outcomes in fetuses diagnosed with congenital urinary tract anomalies

Sonja Pop-Trajkovic Dinic1, Radomir Zivadinovic1, Milan Stefanovic1, Milan Trenkic1, Jelena Milosevic1, Dejan Mitic1
DOI: 10.5603/GP.a2021.0032
·
Pubmed: 33844244
·
Ginekol Pol 2021;92(9):607-610.
Affiliations
  1. Clinic for Gynecology and Obstetrics, Clinical Center of Niš, Serbia

open access

Vol 92, No 9 (2021)
ORIGINAL PAPERS Gynecology
Published online: 2021-04-08

Abstract

Objectives: Urinary tract anomalies account for approximately one-quarter of all antenatally detected anomalies. The aim of this study was to identify factors associated with severe adverse neonatal outcomes of a prenatally diagnosed urinary tract anomaly.
Material and methods: A retrospective-prospective study included 101 pregnant women with prenatally diagnosed fetal urinary tract anomalies presented to the Council for Fetal Anomalies. Prenatal diagnoses were compared with autopsy findings in cases of terminated pregnancy or with clinical and operative findings of the infants.
Results: The mortality rate in the group of patients with fetal obstructive uropathy (60 patients) was 10% and in the group of patients with fetal multicystic dysplastic kidney (38 patients) 15.7%. Surgery was performed on 53.4% of the children, whereas more than half of the operations involved resolving associated urinary tract anomalies. Postoperative renal function deterioration occurred in 19% of the children.
Conclusions: The prognosis of renal function in obstructive uropathies is excellent if oligoamnios does not develop prenatally and in case of timely provided surgical care is provided postnatally. The finding of the bilateral multicystic dysplastic kidney is associated with poor prognosis. The prognosis in fetal unilateral multicystic dysplastic kidney depends primarily on the condition of the contralateral kidney and the existence of associated anomalies.

Abstract

Objectives: Urinary tract anomalies account for approximately one-quarter of all antenatally detected anomalies. The aim of this study was to identify factors associated with severe adverse neonatal outcomes of a prenatally diagnosed urinary tract anomaly.
Material and methods: A retrospective-prospective study included 101 pregnant women with prenatally diagnosed fetal urinary tract anomalies presented to the Council for Fetal Anomalies. Prenatal diagnoses were compared with autopsy findings in cases of terminated pregnancy or with clinical and operative findings of the infants.
Results: The mortality rate in the group of patients with fetal obstructive uropathy (60 patients) was 10% and in the group of patients with fetal multicystic dysplastic kidney (38 patients) 15.7%. Surgery was performed on 53.4% of the children, whereas more than half of the operations involved resolving associated urinary tract anomalies. Postoperative renal function deterioration occurred in 19% of the children.
Conclusions: The prognosis of renal function in obstructive uropathies is excellent if oligoamnios does not develop prenatally and in case of timely provided surgical care is provided postnatally. The finding of the bilateral multicystic dysplastic kidney is associated with poor prognosis. The prognosis in fetal unilateral multicystic dysplastic kidney depends primarily on the condition of the contralateral kidney and the existence of associated anomalies.

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Keywords

fetus; congenital; urinary tract; anomalies; outcome

About this article
Title

Predictors of poor neonatal outcomes in fetuses diagnosed with congenital urinary tract anomalies

Journal

Ginekologia Polska

Issue

Vol 92, No 9 (2021)

Article type

Research paper

Pages

607-610

Published online

2021-04-08

DOI

10.5603/GP.a2021.0032

Pubmed

33844244

Bibliographic record

Ginekol Pol 2021;92(9):607-610.

Keywords

fetus
congenital
urinary tract
anomalies
outcome

Authors

Sonja Pop-Trajkovic Dinic
Radomir Zivadinovic
Milan Stefanovic
Milan Trenkic
Jelena Milosevic
Dejan Mitic

References (21)
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