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Misoprostol vaginal insert and Foley catheter in labour induction — single center retrospective observational study of obstetrical outcome
, 1, 1, 2, 2, 1
Affiliations- Collegium Medicum, Jan Kochanowski Univeristy, Kielce, Poland
- ESKULAP Student Scientific Organization - Collegium Medicum, Jan Kochanowski University, Kielce, Poland
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Abstract
Objectives: Induction of labour is one of the most common procedures used in obstetrics and its prevalence tends to
increase. In patients with an unripe cervix (Bishop score < 7) pre-induction procedures are used before the start of oxytocin
induction. Currently there is no consensus among scientific societies on the optimal way of pre-induction. We have conducted
a single-centre retrospective observational study comparing obstetric induction results of patients after 37 weeks
of gestation who were pre-induced with misoprostol vaginal insert (MVI) with 200 μg of misoprostol (Misodel — Ferring
Pharmaceuticals Poland) or Foley catheter (20 F, 60 mL baloon).
Material and methods: We have reviewed the medical records of 503 patients (group A pre-induced MVI — 135 patients,
group B pre-induced Foley catheter — 368 patients) who were in a single, full-term pregnancy, pre-induced due to unripe
cervixes (Bishop score < 7) with a Foley catheter or Misodel (MVI 200 μg). We compared obstetric results between groups.
Results: Group A patients had a lower chance of using oxytocin in labour induction/augmentation (OR = 0.21 95%
CI = 0.13–0.32), and a greater chance of surgical delivery by caesarean section (OR = 2.14 95% CI = 1.42–3.23) and vacuum
extraction (OR = 3.29 95% CI = 1.08–10.00). Group A patients also had a greater chance of abnormal CTG (OR = 2.66 95%
CI = 1.5–4.7) compared to group B. The groups did not differ in terms of meconium stained amniotic fluid and postpartum
haemorrhage. The percentage of children born with a pH from umbilical cord blood < 7.2 and < 7.1 and newborns of
medium general condition (Apgar 4–7) did not differ between the groups.
Conclusions: Neonatological results of children from Foley catheters and MVI induced delivery do not differ. Patients
pre-induced with MVI rarely require labour augmentation with oxytocin. MVI-preinduced patients have a better chance of
having a delivery by CS or VE compared to the Foley catheter.
Abstract
Objectives: Induction of labour is one of the most common procedures used in obstetrics and its prevalence tends to
increase. In patients with an unripe cervix (Bishop score < 7) pre-induction procedures are used before the start of oxytocin
induction. Currently there is no consensus among scientific societies on the optimal way of pre-induction. We have conducted
a single-centre retrospective observational study comparing obstetric induction results of patients after 37 weeks
of gestation who were pre-induced with misoprostol vaginal insert (MVI) with 200 μg of misoprostol (Misodel — Ferring
Pharmaceuticals Poland) or Foley catheter (20 F, 60 mL baloon).
Material and methods: We have reviewed the medical records of 503 patients (group A pre-induced MVI — 135 patients,
group B pre-induced Foley catheter — 368 patients) who were in a single, full-term pregnancy, pre-induced due to unripe
cervixes (Bishop score < 7) with a Foley catheter or Misodel (MVI 200 μg). We compared obstetric results between groups.
Results: Group A patients had a lower chance of using oxytocin in labour induction/augmentation (OR = 0.21 95%
CI = 0.13–0.32), and a greater chance of surgical delivery by caesarean section (OR = 2.14 95% CI = 1.42–3.23) and vacuum
extraction (OR = 3.29 95% CI = 1.08–10.00). Group A patients also had a greater chance of abnormal CTG (OR = 2.66 95%
CI = 1.5–4.7) compared to group B. The groups did not differ in terms of meconium stained amniotic fluid and postpartum
haemorrhage. The percentage of children born with a pH from umbilical cord blood < 7.2 and < 7.1 and newborns of
medium general condition (Apgar 4–7) did not differ between the groups.
Conclusions: Neonatological results of children from Foley catheters and MVI induced delivery do not differ. Patients
pre-induced with MVI rarely require labour augmentation with oxytocin. MVI-preinduced patients have a better chance of
having a delivery by CS or VE compared to the Foley catheter.
Keywords
misoprostol; induction of labour; dinoproston; cervical ripening; Foley catheter
About this articleTitle
Misoprostol vaginal insert and Foley catheter in labour induction — single center retrospective observational study of obstetrical outcome
Journal
Issue
Article type
Research paper
Pages
700-703
Published online
2020-09-18
Page views
1070
Article views/downloads
1129
DOI
Pubmed
Bibliographic record
Ginekol Pol 2020;91(11):700-703.
Keywords
misoprostol
induction of labour
dinoproston
cervical ripening
Foley catheter
Authors
Jakub Mlodawski
Marta Mlodawska
Justyna Plusajska
Jagoda Galuszewska
Kamila Glijer
Stanislaw Gluszek
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