open access

Vol 91, No 11 (2020)
Research paper
Published online: 2020-11-30
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Assessment of renal volume by 3D VOCAL Ultrasonography method in late-onset growth-restricted fetuses with normal amniotic fluid index

Duygu Adıyaman1, Melda Kuyucu1, Bahar Konuralp Atakul1, Hakan Gölbaşı1, Halil Gürsoy Pala1
DOI: 10.5603/GP.2020.0113
·
Pubmed: 33301162
·
Ginekol Pol 2020;91(11):679-684.
Affiliations
  1. Tepecik Training and Research Hospital, Department of Obstetrics and Gynecology, Division of Perinatology, Izmir, Turkey.

open access

Vol 91, No 11 (2020)
ORIGINAL PAPERS Obstetrics
Published online: 2020-11-30

Abstract

Objectives: The aim of this study was to study renal volumetric alterations and renal artery doppler changes in late-onset
fetal growth restricted (FGR) fetuses with normal amniotic fluid compared to healthy pregnancies.
Material and methods: This prospective study was composed of pregnant women with late-onset FGR and a control group
of uncomplicated pregnancies within 32–37 weeks of gestation. Following the assessment of umbilical, bilateral uterine,
middle cerebral using Doppler Ultrasonography (US), three dimensional (3D) US Virtual Organ Computer-aided Analysis
(VOCAL) was executed to calculate bilateral renal volumes.
Results: A total of 76 fetuses with FGR and 51 healthy fetuses (control group) were evaluated. Umbilical artery Doppler
systole/diastole and Pulsatility index values were found to be significantly different between the two groups (p = 0.001 and
p = 0.001, respectively). Middle cerebral, bilateral uterine, and bilateral renal arteries’ Doppler indices revealed no difference
between the two groups. Right, left, and mean renal volume of the fetuses with FGR were smaller than the control
group, and the differences were statistically significant (p = 0.025, p = 0.004, p = 0.004, respectively). Left renal volume was
significantly greater than the right renal volume in the control group (p = 0.009).
Conclusion: Although not accompanied by oligohydramnios, and having similar renal vascular resistance as the control
group, renal volumes of fetuses with late-onset FGR were still observed lower than the control group. This difference was
explained by not decreased blood flow via redistribution but other mechanisms like glomeruli reduction and glomerular
apoptosis.

Abstract

Objectives: The aim of this study was to study renal volumetric alterations and renal artery doppler changes in late-onset
fetal growth restricted (FGR) fetuses with normal amniotic fluid compared to healthy pregnancies.
Material and methods: This prospective study was composed of pregnant women with late-onset FGR and a control group
of uncomplicated pregnancies within 32–37 weeks of gestation. Following the assessment of umbilical, bilateral uterine,
middle cerebral using Doppler Ultrasonography (US), three dimensional (3D) US Virtual Organ Computer-aided Analysis
(VOCAL) was executed to calculate bilateral renal volumes.
Results: A total of 76 fetuses with FGR and 51 healthy fetuses (control group) were evaluated. Umbilical artery Doppler
systole/diastole and Pulsatility index values were found to be significantly different between the two groups (p = 0.001 and
p = 0.001, respectively). Middle cerebral, bilateral uterine, and bilateral renal arteries’ Doppler indices revealed no difference
between the two groups. Right, left, and mean renal volume of the fetuses with FGR were smaller than the control
group, and the differences were statistically significant (p = 0.025, p = 0.004, p = 0.004, respectively). Left renal volume was
significantly greater than the right renal volume in the control group (p = 0.009).
Conclusion: Although not accompanied by oligohydramnios, and having similar renal vascular resistance as the control
group, renal volumes of fetuses with late-onset FGR were still observed lower than the control group. This difference was
explained by not decreased blood flow via redistribution but other mechanisms like glomeruli reduction and glomerular
apoptosis.

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Keywords

late-onset fetal growth restriction; 3D VOCAL Ultrasonography; renal volume

About this article
Title

Assessment of renal volume by 3D VOCAL Ultrasonography method in late-onset growth-restricted fetuses with normal amniotic fluid index

Journal

Ginekologia Polska

Issue

Vol 91, No 11 (2020)

Article type

Research paper

Pages

679-684

Published online

2020-11-30

DOI

10.5603/GP.2020.0113

Pubmed

33301162

Bibliographic record

Ginekol Pol 2020;91(11):679-684.

Keywords

late-onset fetal growth restriction
3D VOCAL Ultrasonography
renal volume

Authors

Duygu Adıyaman
Melda Kuyucu
Bahar Konuralp Atakul
Hakan Gölbaşı
Halil Gürsoy Pala

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