Vol 92, No 4 (2021)
Review paper
Published online: 2021-03-31

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Comparison of Polish and international guidelines on diet supplements in pregnancy — review

Damian Skrypnik1, Malgorzata Moszak1, Ewa Wender-Ozegowska2, Pawel Bogdanski1
Pubmed: 33844264
Ginekol Pol 2021;92(4):322-330.


Proper nutrition is an important element that determines the course of pregnancy. Unfortunately, the everyday diet is not
always able to cover the increased in pregnancy essential vitamins and minerals requirements. Therefore, pregnant women
often use dietary supplements. This study aimed to compare Polish and international recommendations regarding dietary
supplementation during pregnancy. The Polish Society of Gynaecologists and Obstetricians (PSGO) recommends in every
pregnant woman the dietary supplementation of folates, vitamin D and iodine.
Additionally, the benefits of iron supplementation in pregnant women with anemia or at high risk of developing anemia
are also highlighted. In the light of Polish guidelines, the magnesium supplementation is recommended in the condition
of its reduced level in blood. In the case of limited consumption of DHA (docosahexaenoic acid), Polish guidelines recommend
in pregnant women’s diet, at least 600 mg of DHA every day. Still, in case of the high risk of premature birth — at
least 1000 mg DHA a day during the entire pregnancy period should be taken.

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  1. Ustawa o bezpieczeństwie żywności i żywienia z 25 sierpnia 2006 r. ze zmianami (Dz.U. z 2006 r. Nr 171, poz. 1225 ze zm.).
  2. Dwyer JT, Coates PM, Smith MJ. Dietary Supplements: Regulatory Challenges and Research Resources. Nutrients. 2018; 10(1).
  3. Wender-Ożegowska E, Bomba-Opoń D, Brązert J, et al. Standards of Polish Society of Gynecologists and Obstetricians in management of women with diabetes. Ginekol Pol. 2018; 89(6): 341–350.
  4. Wender-Ożegowska E, Bomba-Opoń D, Brazert J, et al. Polish Gynecological Society.Recommendations of Polish Gynecological Society concerning perinatal care in obese pregnant women. Ginekol Pol. 2012; 83(10): 795–799.
  5. Bomba-Opoń D, Hirnle L, Kalinka J, et al. Folate supplementation during the preconception period, pregnancy and puerperium. Polish Society of Gynecologists and Obstetricians Guidelines. Ginekol Pol. 2017; 88(11): 633–636.
  6. ish Gynecological Society. Rekomendacje skiego Towarzystwa ogicznego w zakresie stosowania witamin i mikroelementów u kobiet planujacych ciażę, ciężarnych i karmiących. Ginekol Pol. 2014; 85: 395–399.
  7. Sicińska E, Jeruszka-Bielak M, Roszkowski W, et al. How is the process of setting micronutrients recommendations reflected in nutrition policies in Poland? The case study of folate. Ann Agric Environ Med. 2018; 25(1): 82–86.
  8. Wang M, Wang ZP, Gao LJ, et al. Maternal body mass index and the association between folic acid supplements and neural tube defects. Acta Paediatr. 2013; 102(9): 908–913.
  9. Tsang BL, Devine OJ, Cordero AM, et al. Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and blood folate concentrations: a systematic review and meta-analysis of trials and observational studies. Am J Clin Nutr. 2015; 101(6): 1286–1294.
  10. Li Z, Ye R, Zhang Le, et al. Folic acid supplementation during early pregnancy and the risk of gestational hypertension and preeclampsia. Hypertension. 2013; 61(4): 873–879.
  11. Wen SWu, Guo Y, Rodger M, et al. Folic Acid Supplementation in Pregnancy and the Risk of Pre-Eclampsia-A Cohort Study. PLoS One. 2016; 11(2): e0149818.
  12. Bean LJH, Allen EG, Tinker SW, et al. Lack of maternal folic acid supplementation is associated with heart defects in Down syndrome: a report from the National Down Syndrome Project. Birth Defects Res A Clin Mol Teratol. 2011; 91(10): 885–893.
  13. Jędrzejczak J, Bomba-Opoń D, Jakiel G, et al. Managing epilepsy in women of childbearing age - Polish Society of Epileptology and Polish Gynecological Society Guidelines. Ginekol Pol. 2017; 88(5): 278–284.
  14. Parker SE, Yazdy MM, Tinker SC, et al. The impact of folic acid intake on the association among diabetes mellitus, obesity, and spina bifida. Am J Obstet Gynecol. 2013; 209(3): 239.e1–239.e8.
  15. Salvig JD, Lamont RF. Evidence regarding an effect of marine n-3 fatty acids on preterm birth: a systematic review and meta-analysis. Acta Obstet Gynecol Scand. 2011; 90(8): 825–838.
  16. Poreba R, Drews K, Karowicz-Bilińska A, et al. Polish Gynecological Society. Expert review of Polish Gynecological Society regarding micronutrient supplementation in pregnancy. Ginekol Pol. 2011; 82(7): 550–553.
  17. Dębski R, Hus I, Kotarski J, et al. Statement of the Polish Gynecological Society Expert Group on the prevention of iron deficiency and of anemia caused by iron deficiency with a low dose heme iron in women. State of the art, 2013. Ginekol Pol. 2014; 85(1): 74–78.
  18. Pavord S, Myers B, Robinson S, et al. British Committee for Standards in Haematology. UK guidelines on the management of iron deficiency in pregnancy. Br J Haematol. 2012; 156(5): 588–600.
  19. Horvath A, Koletzko B, Szajewska H. Effect of supplementation of women in high-risk pregnancies with long-chain polyunsaturated fatty acids on pregnancy outcomes and growth measures at birth: a meta-analysis of randomized controlled trials. Br J Nutr. 2007; 98(2): 253–259.
  20. Charzewska J, Chlebna-Sokół D, Chybicka A, et al. Prophylaxis of vitamin D deficiency - Polishrecommendation2009. Ginekol Pol. 2010; 81(2): 149–153.
  21. Płudowski P, Karczmarewicz E, Bayer M, et al. Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe - recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency. Endokrynol Pol. 2013; 64(4): 319–327.
  22. Alwan NA, Greenwood DC, Simpson NAB, et al. The relationship between dietary supplement use in late pregnancy and birth outcomes: a cohort study in British women. BJOG. 2010; 117(7): 821–829.
  23. American College of ricians and ogists Committee on ric Practice Society for Maternal-Fetal Medicine. Committee Opinion No. 573: Magnesium sulfate use in obstetrics. Obstet Gynecol. 2013; 122(3): 727–728.
  24. Szybiński Z. Polish Council for Control of Iodine Deficiency Disorders. Work of the Polish Council for Control of Iodine Deficiency Disorders, and the model of iodine prophylaxis in Poland. Endokrynol Pol. 2012; 63(2): 156–160.
  25. Gautam SC, Saha L, Sekhri K, et al. Iron deficiency in pregnancy and the rationality of iron supplements prescribed during pregnancy. Gen scape Gen. Med. 2008; 10(12): 283.
  26. Trofimiuk-Mudlner M, Hubalewska-Dydejczyk A. Iodine Deficiency and Iodine Prophylaxis in Pregnancy. Recent Pat Endocr Metab Immune Drug Discov. 2017; 10(2): 85–95.
  27. de Escobar GM, Obregón MJ, del Rey FE. Iodine deficiency and brain development in the first half of pregnancy. Public Health Nutr. 2007; 10(12A): 1554–1570.
  28. Oken E, Belfort MB. Fish, fish oil, and pregnancy. JAMA. 2010; 304(15): 1717–1718.
  29. Smuts CM, Huang M, Mundy D, et al. A randomized trial of docosahexaenoic acid supplementation during the third trimester of pregnancy. Obstet Gynecol. 2003; 101(3): 469–479.
  30. Couch SC, Crandell J, King I, et al. Associations between long chain polyunsaturated fatty acids and cardiovascular lipid risk factors in youth with type 1 diabetes: SEARCH Nutrition Ancillary Study. J Diabetes Complications. 2017; 31(1): 67–73.
  31. Szajewska H, Horvath A, Koletzko B. Effect of n-3 long-chain polyunsaturated fatty acid supplementation of women with low-risk pregnancies on pregnancy outcomes and growth measures at birth: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2006; 83(6): 1337–1344.
  32. Bednarek W, Karowicz-Bilinska A, Kotarski J. Recommendations of the expert team of Polish Gynaecological Society the use of omega-3 in obstetrics. Ginekol Pol. 2010; 81(6): 467–469.
  33. ACOG Committee Opinion No. 495: Vitamin D: Screening and supplementation during pregnancy. Obstet Gynecol. 2011; 118(1): 197–198.
  34. Toriello HV. Policy and Practice Guideline Committee of the American College of Medical Genetics. Policy statement on folic acid and neural tube defects. Genet Med. 2011; 13(6): 593–596.
  35. RCOG statement: Study claims multivitamin and mineral supplements for pregnant women aren't needed 2016.
  36. Healthy eating and vitamin supplements in pregnancy 2014.
  37. RCOG statement: New NICE public health guidance on Vitamin D supplementation 2014.
  38. NICE guideline. Vitamin D: supplement use in specific population groups 2014.
  39. NICE clinical guideline. Antenatal care for uncomplicated pregnancies 2008 (update 2019).
  40. RCOG. Vitamin D in Pregnancy 2014.