open access
Cerebral palsy and obstetric-neonatological interventions
, 34, 4, 5, 2, 6, 78, 12
Affiliations- Department and Clinic of Obstetrics and Gynaecology, Collegium Medicum Jan Kochanowski University in Kielce
- Department of Obstetrics and Gynaecology, Voivodeship Combined Hospital in Kielce
- Collegium Medicum, Jan Kochanowski Univeristy, Kielce, Poland
- Clinic of Neonatology, Voivodeship Combined Hospital Kielce
- Ujastek Obstetric and Gynecological Hospital, Ujastek 3, 31-752 Cracow, Poland
- Department of Internal Medicine, Voivodeship Combined Hospital in Kielce
- Department of General, Oncological and Endocrinological Surgery, Voivodeship Hospital in Kielce
- Collegium Medicum, Jan Kochanowski University in Kielce, Poland
open access
Abstract
Cerebral palsy is a disease that puts a great mental burden on caregivers and generates very high social costs. Children with
CP require many years of rehabilitation and medical care. The etiology of the disease is undoubtedly multifactorial, and the
pathogenesis is associated with focal damage to the central nervous system. One can find descriptions of well-documented
interventions in the literature that reduce the risk of CP in certain groups of pregnant and neonatal patients, and interventions
that have a potentially protective effect. In this review, we have analyzed the available literature in terms of prenatal
and postnatal interventions that may have an impact on reducing the incidence of this condition in children.
Abstract
Cerebral palsy is a disease that puts a great mental burden on caregivers and generates very high social costs. Children with
CP require many years of rehabilitation and medical care. The etiology of the disease is undoubtedly multifactorial, and the
pathogenesis is associated with focal damage to the central nervous system. One can find descriptions of well-documented
interventions in the literature that reduce the risk of CP in certain groups of pregnant and neonatal patients, and interventions
that have a potentially protective effect. In this review, we have analyzed the available literature in terms of prenatal
and postnatal interventions that may have an impact on reducing the incidence of this condition in children.
Keywords
cerebral palsy; magnesium sulfate; pogesterone; therapeutic hypothermia; Delayed Cord Clamping; antenatal corticosteroids
About this articleTitle
Cerebral palsy and obstetric-neonatological interventions
Journal
Issue
Article type
Review paper
Pages
722-727
Published online
2019-12-31
Page views
2704
Article views/downloads
2033
DOI
Pubmed
Bibliographic record
Ginekol Pol 2019;90(12):722-727.
Keywords
cerebral palsy
magnesium sulfate
pogesterone
therapeutic hypothermia
Delayed Cord Clamping
antenatal corticosteroids
Authors
Jakub Mlodawski
Marta Mlodawska
Grazyna Pazera
Wojciech Michalski
Tomasz Domanski
Magdalena Dolecka-Slusarczyk
Stanislaw Gluszek
Wojciech Rokita
References (35)- Winter S, Autry A, Boyle C, et al. Trends in the prevalence of cerebral palsy in a population-based study. Pediatrics. 2002; 110(6): 1220–1225.
- Hjern A, Thorngren-Jerneck K. Perinatal complications and socio-economic differences in cerebral palsy in Sweden - a national cohort study. BMC Pediatr. 2008; 8: 49.
- Kornacka MK, Bokiniec R, Bargiel A. [Risk factors for preterm encephalopathy]. Ginekol Pol. 2009; 80(8): 620–623.
- Strijbis EMM, Oudman I, van Essen P, et al. Cerebral palsy and the application of the international criteria for acute intrapartum hypoxia. Obstet Gynecol. 2006; 107(6): 1357–1365.
- Pharoah PO, Cooke T, Rosenbloom L. Acquired cerebral palsy. Arch Dis Child. 1989; 64(7): 1013–1016.
- Hankins G. Defining the pathogenesis and pathophysiology of neonatal encephalopathy and cerebral palsy. Obstetrics & Gynecology. 2003; 102(3): 628–636.
- Strijbis EMM, Oudman I, van Essen P, et al. Cerebral palsy and the application of the international criteria for acute intrapartum hypoxia. Obstet Gynecol. 2006; 107(6): 1357–1365.
- Dodd JM, Jones L, Flenady V, et al. Prenatal administration of progesterone for preventing preterm birth in women considered to be at risk of preterm birth. Cochrane Database Syst Rev. 2013(7): CD004947.
- Bomba-Opoń D, Czajkowski K, Karowicz-Bilińska A, et al. Polish Gynecological Society. [Recommendations of the Polish Gynecological Society concerning application of progesterone in obstetrics and gynecology]. Ginekol Pol. 2015; 86(3): 234–238.
- Romero R, Nicolaides KH, Conde-Agudelo A, et al. Vaginal progesterone decreases preterm birth ≤ 34 weeks of gestation in women with a singleton pregnancy and a short cervix: an updated meta-analysis including data from the OPPTIMUM study. Ultrasound Obstet Gynecol. 2016; 48(3): 308–317.
- Romero R, Conde-Agudelo A, El-Refaie W, et al. Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta-analysis of individual patient data. Ultrasound Obstet Gynecol. 2017; 49(3): 303–314.
- Huras H, Kalinka J, Dębski R. Short cervix in twin pregnancies: current state of knowledge and the proposed scheme of treatment. Ginekol Pol. 2017; 88(11): 626–632.
- Shepherd E, Salam RA, Middleton P, et al. Antenatal and intrapartum interventions for preventing cerebral palsy: an overview of Cochrane systematic reviews. Cochrane Database Syst Rev. 2017; 8: CD012077.
- Alfirevic Z, Stampalija T, Medley N. Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. Cochrane Database Syst Rev. 2017; 6: CD008991.
- Kosinski P, Sarzynska-Nowacka U, Fiolna M, et al. The practical use of acetylsalicylic acid in the era of the ASPRE trial. Update and literature review. Ginekol Pol. 2018; 89(2): 107–111.
- Rolnik DL, Wright D, Poon LC, et al. Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia. N Engl J Med. 2017; 377(7): 613–622.
- Roberts D, Brown J, Medley N, et al. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev. 2017; 3: CD004454.
- Borszewska-Kornacka MK, Gulczyńska E, Kostuch M, et al. Antenatal corticosteroids and respiratory distress syndrome - the first Polish national survey. Ginekol Pol. 2016; 87(7): 498–503.
- Sotiriadis A, Tsiami A, Papatheodorou S, et al. Neurodevelopmental Outcome After a Single Course of Antenatal Steroids in Children Born Preterm: A Systematic Review and Meta-analysis. Obstet Gynecol. 2015; 125(6): 1385–1396.
- Costantine MM, Weiner SJ. Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Effects of antenatal exposure to magnesium sulfate on neuroprotection and mortality in preterm infants: a meta-analysis. Obstet Gynecol. 2009; 114(2 Pt 1): 354–364.
- Costantine MM, Drever N. Antenatal exposure to magnesium sulfate and neuroprotection in preterm infants. Obstet Gynecol Clin North Am. 2011; 38(2): 351–366, xi.
- Doyle LW, Anderson PJ, Haslam R, et al. Australasian Collaborative Trial of Magnesium Sulphate (ACTOMgSO4) Study Group. School-age outcomes of very preterm infants after antenatal treatment with magnesium sulfate vs placebo. JAMA. 2014; 312(11): 1105–1113.
- WHO recommendation on the use of magnesium sulfate for foetal protection from neurological complications; 17 November 2015, The WHO Reproductive Health Library.
- World Health Organization. Guideline: delayed umbilical cord clamping for improved maternal and infant health and nutrition outcomes. 2014.
- Guidelines on basic newborn resuscitation. Geneva: World Health Organization; 2012. http://apps.who.int/iris/bitstream/10665/75157/1/9789241503693_eng.pdf?ua=1 (16.06.2014).
- Mercer JS, Vohr BR, McGrath MM, et al. Delayed cord clamping in very preterm infants reduces the incidence of intraventricular hemorrhage and late-onset sepsis: a randomized, controlled trial. Pediatrics. 2006; 117(4): 1235–1242.
- Fogarty M, Osborn DA, Askie L, et al. Delayed vs early umbilical cord clamping for preterm infants: a systematic review and meta-analysis. Am J Obstet Gynecol. 2018; 218(1): 1–18.
- Rabe H, Diaz-Rossello JL, Duley L, et al. Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes. Cochrane Database Syst Rev. 2012(8): CD003248.
- Guideline: Intermittent iron supplementation in preschool and school-age children. Geneva: World Health Organization; 2011. https://apps.who.int/iris/bitstream/handle/10665/148793/9789241508209_eng.pdf;jsessionid=02EE631FFDF307955726827FCCB2B8AE?sequence=1 .
- McDonald SJ, Middleton P, Dowswell T, et al. Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes. Cochrane Database Syst Rev. 2008; 9(2): CD004074–397.
- Andersson O, Lindquist B, Lindgren M, et al. Effect of Delayed Cord Clamping on Neurodevelopment at 4 Years of Age: A Randomized Clinical Trial. JAMA Pediatr. 2015; 169(7): 631–638.
- Rabe H, Jewison A, Alvarez RF, et al. Brighton Perinatal Study Group. Milking compared with delayed cord clamping to increase placental transfusion in preterm neonates: a randomized controlled trial. Obstet Gynecol. 2011; 117(2 Pt 1): 205–211.
- Tagin MA, Woolcott CG, Vincer MJ, et al. Hypothermia for neonatal hypoxic ischemic encephalopathy: an updated systematic review and meta-analysis. Arch Pediatr Adolesc Med. 2012; 166(6): 558–566.
- Gadzinowski J, Gulczyńska E, Michniewicz B, et al. [Therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy]. Ginekol Pol. 2012; 83(3): 214–218.
- Papile LA, Baley JE, Benitz W, et al. Committee on Fetus and Newborn. Hypothermia and neonatal encephalopathy. Pediatrics. 2014; 133(6): 1146–1150.
