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Ghrelin does not change in hyperemesis gravidarum
- Department of Gynecology and Obstetrics, Health Sciences University, Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey
- YuzuncuDepartment of Gynecology and Obstetrics, Yüzüncüyıl University, VAN, Turkey
- Department of Biochemistry, İzzet Baysal University, Bolu, Turkey
- Department of Gynecology and Obstetrics, İstanbul Science University, Florance Nightingale Hospital, İstanbul, Turkey
- Department of Gynecology and Obstetrics, Dicle University, Diyarbakır, Turkey
- Department of Gynecology and Obstetrics, Akdamar Hospital, VAN, Turkey
open access
Abstract
Objectives: Ghrelin levels can play an important role in maintaining the energy balance of pregnant women. Therefore,
we investigated the relationship between HG and Ghrelin.
Material and methods: 50 female patients admitted to the VAN Yüzüncü Yıl University, Gynecology and Obstetrics Department
were evaluated. The patients were divided into two groups: Group 1 included 25 pregnant women with HG, Group 2
included 25 healthy pregnant women.
Results: The two groups showed similarities in terms of age, gravidity, B-HCG and gestational age. There was no statistically
significant difference between the two groups in terms of the Ghrelin levels (p = 0.867).
Conclusions: This study shows that there is no difference between Ghrelin levels and HG during pregnancy. Increased
Ghrelin in previous studies was attributed to low oral intake. Another study reported lower Ghrelin levels are not the result
of, but are rather the cause of, reduced oral intake during. The balancing of these two conditions does not lead to a change
in the level of Ghrelin.
Abstract
Objectives: Ghrelin levels can play an important role in maintaining the energy balance of pregnant women. Therefore,
we investigated the relationship between HG and Ghrelin.
Material and methods: 50 female patients admitted to the VAN Yüzüncü Yıl University, Gynecology and Obstetrics Department
were evaluated. The patients were divided into two groups: Group 1 included 25 pregnant women with HG, Group 2
included 25 healthy pregnant women.
Results: The two groups showed similarities in terms of age, gravidity, B-HCG and gestational age. There was no statistically
significant difference between the two groups in terms of the Ghrelin levels (p = 0.867).
Conclusions: This study shows that there is no difference between Ghrelin levels and HG during pregnancy. Increased
Ghrelin in previous studies was attributed to low oral intake. Another study reported lower Ghrelin levels are not the result
of, but are rather the cause of, reduced oral intake during. The balancing of these two conditions does not lead to a change
in the level of Ghrelin.
Keywords
Ghrelin; Hyperemesis Gravidarum; Etiopathogenesis
Title
Ghrelin does not change in hyperemesis gravidarum
Journal
Issue
Article type
Research paper
Pages
699-701
Published online
2019-12-31
Page views
1332
Article views/downloads
918
DOI
Pubmed
Bibliographic record
Ginekol Pol 2019;90(12):699-701.
Keywords
Ghrelin
Hyperemesis Gravidarum
Etiopathogenesis
Authors
Serhat Ege
Ali Kolusarı
Güler Buğdaycı
Numan Çim
Muhammet Hanifi Bademkıran
Nurullah Peker
Selami Erdem
Çağdaş Özgökçe
Recep Yıldızhan
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