open access

Vol 89, No 7 (2018)
Research paper
Published online: 2018-07-31
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Brenner tumor of the ovary — ultrasound features and clinical management of a rare ovarian tumor mimicking ovarian cancer

Vit Weinberger1, Luboš Minář, Michal Felsinger, Petra Ovesná, Markéta Bednaříková, Marta Číhalová, Eva Jandáková, Jitka Hausnerová, Barbora Chaloupková, Michal Zikán
DOI: 10.5603/GP.a2018.0061
·
Pubmed: 30091444
·
Ginekol Pol 2018;89(7):357-363.
Affiliations
  1. University Hospital Brno, Department of Obstetrics and Gynecology, Medical Faculty, Masaryk University, Jihlavska 20, 62500 Brno, Czech Republic

open access

Vol 89, No 7 (2018)
ORIGINAL PAPERS Gynecology
Published online: 2018-07-31

Abstract

  Objectives: To describe the ultrasound features of benign Brenner tumor in the background of complex clinical and histopathological pictures. Material and methods: We retrospectively identified patients with histologically confirmed benign Brenner tumor of the ovary who were treated in our institution in 2003–2016, and for whom complete imaging, clinical, perioperative and histopathological data were available in the database. Ultrasound findings were drawn from images and reports using terms and definitions of the International Ovarian Tumor Analysis group and pattern recognition description was applied. Results: Twenty-three patients were identified, most postmenopausal and asymptomatic. On ultrasound, 19/23 tumors were found unilaterally, 4/23 bilaterally, and 82% of tumors were detected in the left ovary. Most Brenner tumors (16/23) contained solid components and revealed no or minimal blood flow by subjective color score upon Doppler examination (19/23, 83%). Calcifications with shadowing were observed in 57% of all Brenner tumors and in 81% of tumors containing solid components. The complex appearance of the tumor misled the sonographers to describe the mass as malignant in 9 cases (39%), and frozen section was performed perioperatively. Surgery was performed via laparoscopy in 11 (48%) and via laparotomy in 12 (52%) cases. Conclusions: The complexity of the ultrasound picture, consisting of features like calcifications with acoustic shadowing, a poorly vascularized solid mass, and a left-sided localization could be signs of a benign Brenner tumor and could preop­eratively help to differentiate between benign and malignant tumor.

Abstract

  Objectives: To describe the ultrasound features of benign Brenner tumor in the background of complex clinical and histopathological pictures. Material and methods: We retrospectively identified patients with histologically confirmed benign Brenner tumor of the ovary who were treated in our institution in 2003–2016, and for whom complete imaging, clinical, perioperative and histopathological data were available in the database. Ultrasound findings were drawn from images and reports using terms and definitions of the International Ovarian Tumor Analysis group and pattern recognition description was applied. Results: Twenty-three patients were identified, most postmenopausal and asymptomatic. On ultrasound, 19/23 tumors were found unilaterally, 4/23 bilaterally, and 82% of tumors were detected in the left ovary. Most Brenner tumors (16/23) contained solid components and revealed no or minimal blood flow by subjective color score upon Doppler examination (19/23, 83%). Calcifications with shadowing were observed in 57% of all Brenner tumors and in 81% of tumors containing solid components. The complex appearance of the tumor misled the sonographers to describe the mass as malignant in 9 cases (39%), and frozen section was performed perioperatively. Surgery was performed via laparoscopy in 11 (48%) and via laparotomy in 12 (52%) cases. Conclusions: The complexity of the ultrasound picture, consisting of features like calcifications with acoustic shadowing, a poorly vascularized solid mass, and a left-sided localization could be signs of a benign Brenner tumor and could preop­eratively help to differentiate between benign and malignant tumor.

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Keywords

Brenner tumor, ovarian neoplasms, diagnosis, surgery, ultrasonography

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About this article
Title

Brenner tumor of the ovary — ultrasound features and clinical management of a rare ovarian tumor mimicking ovarian cancer

Journal

Ginekologia Polska

Issue

Vol 89, No 7 (2018)

Article type

Research paper

Pages

357-363

Published online

2018-07-31

DOI

10.5603/GP.a2018.0061

Pubmed

30091444

Bibliographic record

Ginekol Pol 2018;89(7):357-363.

Keywords

Brenner tumor
ovarian neoplasms
diagnosis
surgery
ultrasonography

Authors

Vit Weinberger
Luboš Minář
Michal Felsinger
Petra Ovesná
Markéta Bednaříková
Marta Číhalová
Eva Jandáková
Jitka Hausnerová
Barbora Chaloupková
Michal Zikán

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