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Vol 89, No 4 (2018)
Research paper
Published online: 2018-04-30
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Ascites Index — a novel technique to evaluate ascites in ovarian hyperstimulation syndrome: a concept-proof study

Piotr Robert Szkodziak1, Piotr Czuczwar1, Wojciech Wrona1, Tomasz Paszkowski1, Filip Szkodziak2, Sławomir Woźniak1
DOI: 10.5603/GP.a2018.0031
·
Pubmed: 29781072
·
Ginekol Pol 2018;89(4):183-189.
Affiliations
  1. 3rd Chair and Department of Gynecology Medical University in Lublin, Jaczewskiego 8, 20-954 Lublin, Poland
  2. Student research circle at the 3rd Chair and Department of Gynecology, Medical Univeristy in Lublin, Poland, Jaczewskiego 8, 20-954 Lublin, Poland

open access

Vol 89, No 4 (2018)
ORIGINAL PAPERS Gynecology
Published online: 2018-04-30

Abstract

 Objectives: Controlled ovarian hyperstimulation is an important step in infertility treatment. In some cases, however, ovar­ian hyperstimulation syndrome (OHSS) can occur. In its severe forms, ascites is likely to develop, associated with dyspnea. The aim of this study was to explore the usefulness of Ascites Index (AsI), a new tool for quantitative determination of ascites in patients with OHSS, to obtain data for planning further trials.

Material and methods: Twelve patients with OHSS and ascites were included in the study. All patients were admitted to the hospital because of abdominal pain and dyspnea due to increasing ascites. Ultrasound measurements of ascites extent were performed in four external quadrants of the abdomen. Pockets of free fluid were measured. The obtained values were totaled, forming the Ascites Index (AsI), similarly to the amniotic fluid index. Because of dyspnea, paracentesis was performed in all cases.

Results: Median AsI at which patients reported dyspnea was 29.0 cm (range 21.6–38.6 cm). At AsI values less than 21.6 cm, no dyspnea was observed in any of the 12 studied patients. To avoid complications, 2000 mL of ascitic fluid was collected in each patient. After paracentesis, range of AsI decreased to 12.1–14.5 cm.

Conclusions: The proposed AsI seems to be a promising tool for estimating and monitoring the ascites extent in OHSS. It can be estimated using basic ultrasound equipment. AsI requires further studies for standardization and transferability to other causes of ascites.

Abstract

 Objectives: Controlled ovarian hyperstimulation is an important step in infertility treatment. In some cases, however, ovar­ian hyperstimulation syndrome (OHSS) can occur. In its severe forms, ascites is likely to develop, associated with dyspnea. The aim of this study was to explore the usefulness of Ascites Index (AsI), a new tool for quantitative determination of ascites in patients with OHSS, to obtain data for planning further trials.

Material and methods: Twelve patients with OHSS and ascites were included in the study. All patients were admitted to the hospital because of abdominal pain and dyspnea due to increasing ascites. Ultrasound measurements of ascites extent were performed in four external quadrants of the abdomen. Pockets of free fluid were measured. The obtained values were totaled, forming the Ascites Index (AsI), similarly to the amniotic fluid index. Because of dyspnea, paracentesis was performed in all cases.

Results: Median AsI at which patients reported dyspnea was 29.0 cm (range 21.6–38.6 cm). At AsI values less than 21.6 cm, no dyspnea was observed in any of the 12 studied patients. To avoid complications, 2000 mL of ascitic fluid was collected in each patient. After paracentesis, range of AsI decreased to 12.1–14.5 cm.

Conclusions: The proposed AsI seems to be a promising tool for estimating and monitoring the ascites extent in OHSS. It can be estimated using basic ultrasound equipment. AsI requires further studies for standardization and transferability to other causes of ascites.

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Keywords

Ascites Index, ascites, ascites evaluation, ovarian hyperstimulation syndrome

About this article
Title

Ascites Index — a novel technique to evaluate ascites in ovarian hyperstimulation syndrome: a concept-proof study

Journal

Ginekologia Polska

Issue

Vol 89, No 4 (2018)

Article type

Research paper

Pages

183-189

Published online

2018-04-30

Page views

2677

Article views/downloads

2921

DOI

10.5603/GP.a2018.0031

Pubmed

29781072

Bibliographic record

Ginekol Pol 2018;89(4):183-189.

Keywords

Ascites Index
ascites
ascites evaluation
ovarian hyperstimulation syndrome

Authors

Piotr Robert Szkodziak
Piotr Czuczwar
Wojciech Wrona
Tomasz Paszkowski
Filip Szkodziak
Sławomir Woźniak

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