open access

Vol 89, No 1 (2018)
Research paper
Published online: 2018-01-31
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Does reactive hypoglycemia during the 100 g oral glucose tolerance test adversely affect perinatal outcomes?

Ilhan Bahri Delibas, Sema Tanriverdi, Bulent Cakmak
DOI: 10.5603/GP.a2018.0005
·
Pubmed: 29411343
·
Ginekol Pol 2018;89(1):25-29.

open access

Vol 89, No 1 (2018)
ORIGINAL PAPERS Obstetrics
Published online: 2018-01-31

Abstract

Objectives: To determine whether pregnant women who have reactive hypoglycemia during the 100 g oral glucose toler­ance test (OGTT) are at an increased risk of poor pregnancy outcomes.

Material and methods: We retrospectively analyzed perinatal data from 413 women who underwent a 3 h OGTT at 24–28 weeks of gestation and gave birth in our clinics between January 2012 and December 2014.

Results: According to OGTT results, the majority of the subjects were normoglycemic (n = 316, 76.5%), while 49 (11.9%) were diagnosed with gestational diabetes, and 33 (8.0%) had single high glucose values. Reactive hypoglycemia was de­tected in only 15 patients (3.6%). The mean age of the women in the reactive hypoglycemia group was significantly lower than that of the women in the gestational diabetes and single high glucose value groups (26.4 ± 4.4 years, 31.4 ± 5.4 years, and 31.8 ± 4.3 years, respectively; p < 0.05). The newborns of the women in the reactive hypoglycemia group had higher rates of APGAR scores < 7, increased admission to the neonatal intensive care unit (NICU), and lower birth weights compared with the other groups (p < 0.001, p < 0.001, and p = 0.009, respectively).

Conclusion: Reactive hypoglycemia during the 3 h 100 g OGTT is significantly associated with low APGAR scores, low birth weights, and prenatal admission to the NICU. Therefore, pregnant women who develop hypoglycemia during the 100 g OGTT performed at 24–28 weeks of gestation should receive attentive follow-up care to decrease the possibility of adverse perinatal outcomes.

Abstract

Objectives: To determine whether pregnant women who have reactive hypoglycemia during the 100 g oral glucose toler­ance test (OGTT) are at an increased risk of poor pregnancy outcomes.

Material and methods: We retrospectively analyzed perinatal data from 413 women who underwent a 3 h OGTT at 24–28 weeks of gestation and gave birth in our clinics between January 2012 and December 2014.

Results: According to OGTT results, the majority of the subjects were normoglycemic (n = 316, 76.5%), while 49 (11.9%) were diagnosed with gestational diabetes, and 33 (8.0%) had single high glucose values. Reactive hypoglycemia was de­tected in only 15 patients (3.6%). The mean age of the women in the reactive hypoglycemia group was significantly lower than that of the women in the gestational diabetes and single high glucose value groups (26.4 ± 4.4 years, 31.4 ± 5.4 years, and 31.8 ± 4.3 years, respectively; p < 0.05). The newborns of the women in the reactive hypoglycemia group had higher rates of APGAR scores < 7, increased admission to the neonatal intensive care unit (NICU), and lower birth weights compared with the other groups (p < 0.001, p < 0.001, and p = 0.009, respectively).

Conclusion: Reactive hypoglycemia during the 3 h 100 g OGTT is significantly associated with low APGAR scores, low birth weights, and prenatal admission to the NICU. Therefore, pregnant women who develop hypoglycemia during the 100 g OGTT performed at 24–28 weeks of gestation should receive attentive follow-up care to decrease the possibility of adverse perinatal outcomes.

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Keywords

Gestational diabetes, oral glucose tolerance test, perinatal outcome, pregnancy, reactive hypoglycemia

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Title

Does reactive hypoglycemia during the 100 g oral glucose tolerance test adversely affect perinatal outcomes?

Journal

Ginekologia Polska

Issue

Vol 89, No 1 (2018)

Article type

Research paper

Pages

25-29

Published online

2018-01-31

DOI

10.5603/GP.a2018.0005

Pubmed

29411343

Bibliographic record

Ginekol Pol 2018;89(1):25-29.

Keywords

Gestational diabetes
oral glucose tolerance test
perinatal outcome
pregnancy
reactive hypoglycemia

Authors

Ilhan Bahri Delibas
Sema Tanriverdi
Bulent Cakmak

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