open access

Vol 88, No 11 (2017)
Research paper
Published online: 2017-11-30
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Comparison of the effectiveness of topical silicone gel and corticosteroid cream on the pfannenstiel scar prevention — a randomized controlled trial

Elif Meseci1, Semra Kayatas2, Murat Api3, Aysen Boza4, Muzaffer Seyhan Cikman2
DOI: 10.5603/GP.a2017.0107
·
Pubmed: 29303212
·
Ginekol Pol 2017;88(11):591-598.
Affiliations
  1. Acıbadem Kozyatagı Hospital, Department of Obstetrics and Gynecology, Inonu Caddesi, Okur Sokak, No:20 Kozyatagı, 34742 Istanbul, Turkey
  2. Zeynep Kamil Maternity and Children's Diseases Training and Research Hospital, Department of Obstetrics and Gynecology, Uskudar Opr. Dr. Burhanettin Ustunel Cad. No:10, 34668 Istanbul, Turkey
  3. Medipol University, Faculty of Medicine, Department of Obstetrics and Gynecology, TEM Avrupa Otoyolu Goztepe CıkıSı No: 1 Bagcılar, 34214 Istanbul, Turkey
  4. VKV American Hospital, Department of Obstetrics and Gynecology, Guzelbahce Sok, No:20, Nisantası, 34365 Istanbul, Turkey

open access

Vol 88, No 11 (2017)
ORIGINAL PAPERS Gynecology
Published online: 2017-11-30

Abstract

Objectives: To compare the effects of topical silicone gel and corticosteroid cream for preventing hypertrophic scar and keloid formation following Pfannenstiel incisions.

Material and methods: Fifty patients operated for benign gynecological diseases through primary Pfannenstiel incision were included. The wounds were randomly allocated to the treatment and control arms. In the treatment arm, the wounds were divided into two halves; one was treated with silicone gel and the other with methylprednisolone cream. No treat­ment was administered to the control group. Scars using the modified Vancouver Scar Scale (MVSS), patient satisfaction, and side effects were evaluated before and after (3rd month when treatment discontinued and 6th month) the treatment.

Results: Thirty-nine patients (21 patients in the treatment group and 18 patients in the control group) completed the stu­dy. Intragroup comparisons of the 3rd month and 6th month scores of the MVSS revealed that the scores of all parameters (height, pigmentation, vascularity, pliability, and total MVSS score) significantly decreased at the 6th month evaluation as compared with the 3rd month evaluation in all groups (control, silicone, and methylprednisolone groups). Multiple group comparisons at the 6th month revealed that the most prominent improvements occurred in the methylprednisolone group in all MVSS parameters as compared with the control group and in the height, vascularity, and pigmentation parameters as compared with the silicone group. No side effects were experienced by the patients with either treatment and patient satisfaction was higher in the methylprednisolone group.

Conclusion: The use of topical methylprednisolone cream in fresh wounds at the postoperative early period appears to be promising.

Abstract

Objectives: To compare the effects of topical silicone gel and corticosteroid cream for preventing hypertrophic scar and keloid formation following Pfannenstiel incisions.

Material and methods: Fifty patients operated for benign gynecological diseases through primary Pfannenstiel incision were included. The wounds were randomly allocated to the treatment and control arms. In the treatment arm, the wounds were divided into two halves; one was treated with silicone gel and the other with methylprednisolone cream. No treat­ment was administered to the control group. Scars using the modified Vancouver Scar Scale (MVSS), patient satisfaction, and side effects were evaluated before and after (3rd month when treatment discontinued and 6th month) the treatment.

Results: Thirty-nine patients (21 patients in the treatment group and 18 patients in the control group) completed the stu­dy. Intragroup comparisons of the 3rd month and 6th month scores of the MVSS revealed that the scores of all parameters (height, pigmentation, vascularity, pliability, and total MVSS score) significantly decreased at the 6th month evaluation as compared with the 3rd month evaluation in all groups (control, silicone, and methylprednisolone groups). Multiple group comparisons at the 6th month revealed that the most prominent improvements occurred in the methylprednisolone group in all MVSS parameters as compared with the control group and in the height, vascularity, and pigmentation parameters as compared with the silicone group. No side effects were experienced by the patients with either treatment and patient satisfaction was higher in the methylprednisolone group.

Conclusion: The use of topical methylprednisolone cream in fresh wounds at the postoperative early period appears to be promising.

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Keywords

cicatrix, methyl prednisolonate, silicone gel, topical administration, wound healing

About this article
Title

Comparison of the effectiveness of topical silicone gel and corticosteroid cream on the pfannenstiel scar prevention — a randomized controlled trial

Journal

Ginekologia Polska

Issue

Vol 88, No 11 (2017)

Article type

Research paper

Pages

591-598

Published online

2017-11-30

DOI

10.5603/GP.a2017.0107

Pubmed

29303212

Bibliographic record

Ginekol Pol 2017;88(11):591-598.

Keywords

cicatrix
methyl prednisolonate
silicone gel
topical administration
wound healing

Authors

Elif Meseci
Semra Kayatas
Murat Api
Aysen Boza
Muzaffer Seyhan Cikman

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