open access

Vol 88, No 9 (2017)
Research paper
Published online: 2017-09-29
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Strategy and early results of treatment of advanced cervical cancer patients with synchronous cancers observed in PET-CT imaging

Michał Płachta1, Witold Cholewiński23, Ewa Burchardt1, Paulina Cegła2, Bartosz Urbański13, Żaneta Wareńczak-Florczak13, Andrzej Roszak13
DOI: 10.5603/GP.a2017.0087
·
Pubmed: 29057432
·
Ginekol Pol 2017;88(9):475-480.
Affiliations
  1. Department of Radiotherapy and Oncological Gynecology, Greater Poland Cancer Center, Poznań, Poland, ul. Garbary 15, 61-866 Poznań, Poland
  2. Department of Nuclear Medicine, Greater Poland Cancer Center, Poznań, Poland, ul. Garbary 15, 61-866 Poznań, Poland
  3. Department of Electroradiology, Poznań University of Medical Sciences, Poznań, Poland, ul. Garbary 15, 61-866 Poznań, Poland

open access

Vol 88, No 9 (2017)
ORIGINAL PAPERS Gynecology
Published online: 2017-09-29

Abstract

Objectives: The aim of this study was to present strategy and early results of treatment of advanced cervical cancer patients with synchronous cancers observed in PET-CT imaging, treated at the Greater Poland Cancer Center.

Material and methods: The study included a group of 200 patients with diagnosed stage IIB-IIIB cervical cancer who received PET-CT for the purpose of radiotherapy treatment planning.

Results: Among our study group, four patients (2%) were found to have a synchronous cancer. Two of the cases were diagnosed as breast cancer. However, cancers diagnosed in the other two patients were head and neck malignancies — hypopharyngeal and laryngeal cancer. The choice of an optimal therapeutic approach requires taking into account characteristics of particular malignancies, their stage and histopathology. The whole therapy included radiotherapy of cervical cancer with various combinations of systemic treatment, radiotherapy or surgery of synchronous cancer. According to treatment results, patients diagnosed with breast cancer and hypopharyngeal cancer achieved complete remission of both primary and secondary tumour. Patient diagnosed with laryngeal malignancy, despite achieving complete remission of cervical cancer, finished radiotherapy of the synchronous cancer at a palliative dose.

Conclusions: The growing availability of PET-CT and other imaging methods in cancer diagnosis will increase the number of diagnosed synchronous cancers. Second primary cancers are often detected at an early stage, where radical treatment can be performed for both primary and secondary tumour. However, treatment of such complicated clinical cases as synchronous cancers should be carried out by multidisciplinary teams.

Abstract

Objectives: The aim of this study was to present strategy and early results of treatment of advanced cervical cancer patients with synchronous cancers observed in PET-CT imaging, treated at the Greater Poland Cancer Center.

Material and methods: The study included a group of 200 patients with diagnosed stage IIB-IIIB cervical cancer who received PET-CT for the purpose of radiotherapy treatment planning.

Results: Among our study group, four patients (2%) were found to have a synchronous cancer. Two of the cases were diagnosed as breast cancer. However, cancers diagnosed in the other two patients were head and neck malignancies — hypopharyngeal and laryngeal cancer. The choice of an optimal therapeutic approach requires taking into account characteristics of particular malignancies, their stage and histopathology. The whole therapy included radiotherapy of cervical cancer with various combinations of systemic treatment, radiotherapy or surgery of synchronous cancer. According to treatment results, patients diagnosed with breast cancer and hypopharyngeal cancer achieved complete remission of both primary and secondary tumour. Patient diagnosed with laryngeal malignancy, despite achieving complete remission of cervical cancer, finished radiotherapy of the synchronous cancer at a palliative dose.

Conclusions: The growing availability of PET-CT and other imaging methods in cancer diagnosis will increase the number of diagnosed synchronous cancers. Second primary cancers are often detected at an early stage, where radical treatment can be performed for both primary and secondary tumour. However, treatment of such complicated clinical cases as synchronous cancers should be carried out by multidisciplinary teams.

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Keywords

cervical cancer, synchronous cancer, second primary cancer, PET-CT

About this article
Title

Strategy and early results of treatment of advanced cervical cancer patients with synchronous cancers observed in PET-CT imaging

Journal

Ginekologia Polska

Issue

Vol 88, No 9 (2017)

Article type

Research paper

Pages

475-480

Published online

2017-09-29

DOI

10.5603/GP.a2017.0087

Pubmed

29057432

Bibliographic record

Ginekol Pol 2017;88(9):475-480.

Keywords

cervical cancer
synchronous cancer
second primary cancer
PET-CT

Authors

Michał Płachta
Witold Cholewiński
Ewa Burchardt
Paulina Cegła
Bartosz Urbański
Żaneta Wareńczak-Florczak
Andrzej Roszak

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