Vol 87, No 7 (2016)
Review paper
Published online: 2016-07-29

open access

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Anti-Müllerian hormone: a critical factor for female fertility and reproductive health

Marzena Rzeszowska, Agnieszka Leszcz, Lechosław Putowski, Magdalena Hałabiś, Joanna Tkaczuk-Włach, Jan Kotarski, Grzegorz Polak
Pubmed: 27504948
Ginekol Pol 2016;87(7):532-537.

Abstract

Anti-Müllerian hormone (AMH) is a glycoprotein produced by the granulosa cells of preantral and small antral follicles. AMH concentrations reflect ovarian physiology with high precision, thus serving as a more sensitive marker of the ovarian re­serve than chronological age. This hormone plays a role in the pathogenesis of menstrual disorders and fertility in both obesity and polycystic ovary syndrome. The evaluation of AMH may also be useful in diagnosing or monitoring therapy of granulosa cell ovarian tumors.