open access
Anti-Müllerian hormone: a critical factor for female fertility and reproductive health
open access
Abstract
Anti-Müllerian hormone (AMH) is a glycoprotein produced by the granulosa cells of preantral and small antral follicles. AMH concentrations reflect ovarian physiology with high precision, thus serving as a more sensitive marker of the ovarian reserve than chronological age. This hormone plays a role in the pathogenesis of menstrual disorders and fertility in both obesity and polycystic ovary syndrome. The evaluation of AMH may also be useful in diagnosing or monitoring therapy of granulosa cell ovarian tumors.
Abstract
Anti-Müllerian hormone (AMH) is a glycoprotein produced by the granulosa cells of preantral and small antral follicles. AMH concentrations reflect ovarian physiology with high precision, thus serving as a more sensitive marker of the ovarian reserve than chronological age. This hormone plays a role in the pathogenesis of menstrual disorders and fertility in both obesity and polycystic ovary syndrome. The evaluation of AMH may also be useful in diagnosing or monitoring therapy of granulosa cell ovarian tumors.
Keywords
anti-Müllerian hormone, fertility, gynecology
Title
Anti-Müllerian hormone: a critical factor for female fertility and reproductive health
Journal
Issue
Article type
Review paper
Pages
532-537
Published online
2016-07-29
Page views
3376
Article views/downloads
3002
DOI
Pubmed
Bibliographic record
Ginekol Pol 2016;87(7):532-537.
Keywords
anti-Müllerian hormone
fertility
gynecology
Authors
Marzena Rzeszowska
Agnieszka Leszcz
Lechosław Putowski
Magdalena Hałabiś
Joanna Tkaczuk-Włach
Jan Kotarski
Grzegorz Polak