open access
Transdermal hormone replacement therapy with nanostructured medicines
open access
Abstract
Objectives: Due to hormonal changes during the menopause, women experience a variety of perimenopause and postmenopause symptoms. This review examines the various aspects of nanostructured hormone therapy and its application in the treatments of menopausal symptoms.
Material and methods: Excerpta Medica DataBase, Medical Literature Analysis and Retrieval System Online, Web of Science, and Google Scholar were searched basing on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Seven eligible studies out of 51 related papers, which satisfied the initial search criteria, were extracted and carefully reviewed to clarify the role of nanomedicine in maintaining postmenopausal women’s health.
Results: Review of the seven eligible studies confirmed nanostructured hormone therapy as a safe and effective method for the alleviation of menopausal symptoms. According to the existing studies, nanostructured hormone therapy decreased the mean daily frequency and severity of menopausal symptoms.
Conclusion: The use of transdermal nanoformulations in hormone therapy can relieve climacteric symptoms and prevent other postmenopausal symptoms.
Abstract
Objectives: Due to hormonal changes during the menopause, women experience a variety of perimenopause and postmenopause symptoms. This review examines the various aspects of nanostructured hormone therapy and its application in the treatments of menopausal symptoms.
Material and methods: Excerpta Medica DataBase, Medical Literature Analysis and Retrieval System Online, Web of Science, and Google Scholar were searched basing on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Seven eligible studies out of 51 related papers, which satisfied the initial search criteria, were extracted and carefully reviewed to clarify the role of nanomedicine in maintaining postmenopausal women’s health.
Results: Review of the seven eligible studies confirmed nanostructured hormone therapy as a safe and effective method for the alleviation of menopausal symptoms. According to the existing studies, nanostructured hormone therapy decreased the mean daily frequency and severity of menopausal symptoms.
Conclusion: The use of transdermal nanoformulations in hormone therapy can relieve climacteric symptoms and prevent other postmenopausal symptoms.
Keywords
menopause, hormone therapy, nanostructured medicine
About this articleTitle
Transdermal hormone replacement therapy with nanostructured medicines
Journal
Issue
Article type
Review paper
Pages
103-108
Published online
2017-02-28
Page views
1625
Article views/downloads
2047
DOI
10.5603/GP.a2017.0018
Pubmed
Bibliographic record
Ginekol Pol 2017;88(2):103-108.
Keywords
menopause
hormone therapy
nanostructured medicine
Authors
Fatemeh Abdi
Tayebeh Darooneh
Maryam Ghorbani
Farzaneh Banihashemi
Nasibeh Roozbeh
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