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Vol 6, No 2 (2020)
Review paper
Published online: 2020-09-04
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Rola odporności wrodzonej w twardzinie układowej

Przemysław Jacek Kotyla1, Olga Gumkowska-Sroka2
DOI: 10.5603//FR.2020.0009
·
Forum Reumatol 2020;6(2):70-79.
Affiliations
  1. Katedra i Klinika Chorób Wewnętrznych, Reumatologii i Immunologii Klinicznej Śląskiego Uniwersytetu Medycznego w Katowicach, Ziołowa 45/47, 40-635 Katowice, Poland
  2. Oddział Reumatologii Szpital Wojewódzki nr 5 w Sosnowcu, Pl Medykow 1, 41-200 Sosnowiec, Poland

open access

Vol 6, No 2 (2020)
Review
Published online: 2020-09-04

Abstract

W pracy przedstawiono najnowsze poglądy dotyczące udziału układu odporności wrodzonej w patogenezie twardziny układowej. Szczególną uwagę poświęcono roli receptorów rozpoznających wzorce oraz znaczeniu zjawiska sygnatury interferonu. Wyniki najnowszych badań wskazują także na rosnące znaczenie niektórych populacji komórek odporności wrodzonej jak mastocyty, miofibroblasty oraz komórki NK.

Abstract

W pracy przedstawiono najnowsze poglądy dotyczące udziału układu odporności wrodzonej w patogenezie twardziny układowej. Szczególną uwagę poświęcono roli receptorów rozpoznających wzorce oraz znaczeniu zjawiska sygnatury interferonu. Wyniki najnowszych badań wskazują także na rosnące znaczenie niektórych populacji komórek odporności wrodzonej jak mastocyty, miofibroblasty oraz komórki NK.

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Keywords

twardzina układowa; odporność wrodzona; sygnatura interferonu; limfocyty odpowiedzi nieswoistej

About this article
Title

Rola odporności wrodzonej w twardzinie układowej

Journal

Rheumatology Forum

Issue

Vol 6, No 2 (2020)

Article type

Review paper

Pages

70-79

Published online

2020-09-04

Page views

536

Article views/downloads

297

DOI

10.5603//FR.2020.0009

Bibliographic record

Forum Reumatol 2020;6(2):70-79.

Keywords

twardzina układowa
odporność wrodzona
sygnatura interferonu
limfocyty odpowiedzi nieswoistej

Authors

Przemysław Jacek Kotyla
Olga Gumkowska-Sroka

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