Vol 6, No 1 (2020)
Prace poglądowe
Published online: 2020-07-01
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Relapsing polychondritis

Sonia Kostarczyk-Rogacz, Eugeniusz Józef Kucharz
DOI: 10.5603/FR.2020.0002
·
Forum Reumatologiczne 2020;6(1):10-16.

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Vol 6, No 1 (2020)
Prace poglądowe
Published online: 2020-07-01

Abstract

Relapsing polychondritis (RP) is a rare autoimmune disease with recurrent episodes of inflammation of cartilage of the auricular pinna, nose, larynx, trachea and bronchi, as well as involvement of the inner ear, eye, heart, large vessels, kidneys and skin. Clinical presentation is heterogeneous and diagnostics may be difficult. Therapy includes application of glucocorticoids, immunosuppressants, biologics (tocilizumab and TNF-alpha antagonists). Relapsing polychondritis may lead to a life-threatening damage and obturation of the airways as well as valvular defects and aortic aneurysms.    

Abstract

Relapsing polychondritis (RP) is a rare autoimmune disease with recurrent episodes of inflammation of cartilage of the auricular pinna, nose, larynx, trachea and bronchi, as well as involvement of the inner ear, eye, heart, large vessels, kidneys and skin. Clinical presentation is heterogeneous and diagnostics may be difficult. Therapy includes application of glucocorticoids, immunosuppressants, biologics (tocilizumab and TNF-alpha antagonists). Relapsing polychondritis may lead to a life-threatening damage and obturation of the airways as well as valvular defects and aortic aneurysms.    

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Keywords

cartilage — inflammation; auricular pinna inflammation; obturation of the respiratory tract

About this article
Title

Relapsing polychondritis

Journal

Forum Reumatologiczne

Issue

Vol 6, No 1 (2020)

Pages

10-16

Published online

2020-07-01

DOI

10.5603/FR.2020.0002

Bibliographic record

Forum Reumatologiczne 2020;6(1):10-16.

Keywords

cartilage — inflammation
auricular pinna inflammation
obturation of the respiratory tract

Authors

Sonia Kostarczyk-Rogacz
Eugeniusz Józef Kucharz

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