open access

Vol 3, No 2 (2017)
Przypadki kliniczne
Published online: 2017-06-20
Get Citation

Advanced ankylosing spondylitis diagnosed after infection of the digestive tract — case report

Dorota Suszek, Arkadiusz Koszarny, Maria Majdan, Magdalena Wójcik, Klaudia Tutka, Agnieszka Czukiewska, Paweł Brysiewicz, Katarzyna Bochenek, Mateusz Latek, Kinga Antos-Latek
Forum Reumatologiczne 2017;3(2):102-109.

open access

Vol 3, No 2 (2017)
Przypadki kliniczne
Published online: 2017-06-20

Abstract

Inflammatory spondyloarthrophaties (SpA) are a group of diseases with a close aetiology and clinical course. Infections , especially bacterial, of the digestive tract are possible causes of SpA. Infectious pathogens may penetrate the mucous membrane of the gastrointestinal tract, of the urogenital tracts, respiratory tract and induce the reactive arthritis or exacerbate the previously diagnosed, chronic SpA. Dysbiosis also plays an important role in the pathogenesis of SpA. In the report, authors presented a case of a patient with a long-time backbone pain, in whom Yersinia enterocolitica infection of the digestive tract preceded the peripheral arthritis and inflammatory pain of the spine. The radiological images showed the characteristic changes of the advanced ankylosing spondylitis.

Abstract

Inflammatory spondyloarthrophaties (SpA) are a group of diseases with a close aetiology and clinical course. Infections , especially bacterial, of the digestive tract are possible causes of SpA. Infectious pathogens may penetrate the mucous membrane of the gastrointestinal tract, of the urogenital tracts, respiratory tract and induce the reactive arthritis or exacerbate the previously diagnosed, chronic SpA. Dysbiosis also plays an important role in the pathogenesis of SpA. In the report, authors presented a case of a patient with a long-time backbone pain, in whom Yersinia enterocolitica infection of the digestive tract preceded the peripheral arthritis and inflammatory pain of the spine. The radiological images showed the characteristic changes of the advanced ankylosing spondylitis.

Get Citation

Keywords

infection; digestive tract; spondyloarthritis

About this article
Title

Advanced ankylosing spondylitis diagnosed after infection of the digestive tract — case report

Journal

Forum Reumatologiczne

Issue

Vol 3, No 2 (2017)

Pages

102-109

Published online

2017-06-20

Bibliographic record

Forum Reumatologiczne 2017;3(2):102-109.

Keywords

infection
digestive tract
spondyloarthritis

Authors

Dorota Suszek
Arkadiusz Koszarny
Maria Majdan
Magdalena Wójcik
Klaudia Tutka
Agnieszka Czukiewska
Paweł Brysiewicz
Katarzyna Bochenek
Mateusz Latek
Kinga Antos-Latek

References (12)
  1. Świerkot. J. Spondyloartropatie zapalne. http://www.edukacja.przegladreumatologiczny.pl/spondyloartropatie-zapalne.
  2. Kontny E. Nowe aspekty patogenezy spondyloartropatii zapalnych. Część II – czynniki środowiskowe, zaburzenia mikrobiomu, objawy pozastawowe. Reumatologia 2014; 52. ; 3: 172–180.
  3. Ambarus C, Yeremenko N, Tak PP, et al. Pathogenesis of spondyloarthritis: autoimmune or autoinflammatory? Curr Opin Rheumatol. 2012; 24(4): 351–358.
  4. David T. Astrid van Tubergen. Pathogenesis of spondyloarthritis: . http://www.uptodate com/contents/pathogenesis.
  5. Zubrzycka-Sienkiewicz A. Zmiany w jelitach a zapalenie stawów. Terapia. 2003; 10: 2.
  6. Lahesmaa R, Skurnik M, Toivanen P. Molecular mimicry in the pathogenesis of spondyloarthropathies. A critical appraisal of cross-reactivity between microbial antigens and HLA-B27. Immunol Res. 1993; 12: 193.
  7. Asquith M, Elewaut D, Lin P, et al. The role of the gut and microbes in the pathogenesis of spondyloarthritis. Best Pract Res Clin Rheumatol. 2014; 28(5): 687–702.
  8. Colmegna I, Cuchacovich R, Espinoza LR. HLA-B27-associated reactive arthritis: pathogenetic and clinical considerations. Clin Microbiol Rev. 2004; 17(2): 348–369.
  9. Martínez A, Pacheco-Tena C, Vázquez-Mellado J, et al. Relationship between disease activity and infection in patients with spondyloarthropathies. Ann Rheum Dis. 2004; 63(10): 1338–1340.
  10. Kim GT. Acute exacerbation of ankylosing spondylitis after chlamydial infection in a patient well-controlled with etanercept. Int J Rheum Dis. 2012; 15(5): e113–e115.
  11. Gill T, Asquith M, Rosenbaum JT, et al. The intestinal microbiome in spondyloarthritis. Curr Opin Rheumatol. 2015; 27(4): 319–325.
  12. Colmegna I, Cuchacovich R, Espinoza LR. HLA-B27-Associated Reactive Arthritis: Pathogenetic and Clinical Considerations. Clinical Microbiology Reviews. 2004; 17(2): 348–369.

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl