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ANCA antibodies in ulcerative colitis with coexisting extraintestinal symptoms
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Abstract
ANCA associated vasculitis are a group of connective tissue diseases characterized by a very variable course and clinical presentation. Diagnosis is difficult and complications can lead to disabilities or even death. Standard management often requires long-term immunosuppressive therapy and corticosteroids. ANCA antibodies can be considered as an important biomarker in the diagnosis of this group of vasculitis. However, it is important to remember that there are other diseases where ANCA antibodies can be detected. Ulcerative colitis is one of these diseases and its extra-intestinal symptoms can imitate vasculitis. Presented case report shows diagnostic and therapeutic difficulties occurring in this set of patients.
Abstract
ANCA associated vasculitis are a group of connective tissue diseases characterized by a very variable course and clinical presentation. Diagnosis is difficult and complications can lead to disabilities or even death. Standard management often requires long-term immunosuppressive therapy and corticosteroids. ANCA antibodies can be considered as an important biomarker in the diagnosis of this group of vasculitis. However, it is important to remember that there are other diseases where ANCA antibodies can be detected. Ulcerative colitis is one of these diseases and its extra-intestinal symptoms can imitate vasculitis. Presented case report shows diagnostic and therapeutic difficulties occurring in this set of patients.
Keywords
ANCA antibodies; vasculitis; granulomatosis with polyangiitis; ulcerative colitis; inflammatory bowel diseases
About this articleTitle
ANCA antibodies in ulcerative colitis with coexisting extraintestinal symptoms
Journal
Issue
Article type
Case report
Pages
43-47
Published online
2017-04-19
Page views
435
Article views/downloads
1053
Bibliographic record
Forum Reumatol 2017;3(1):43-47.
Keywords
ANCA antibodies
vasculitis
granulomatosis with polyangiitis
ulcerative colitis
inflammatory bowel diseases
Authors
Błażej Hirsch
Rafał Młynarczyk
Katarzyna Pawlak-Buś
Piotr Leszczyński
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