Interactions of immunosuppressive drugs: why they are so important in clinical practice?

Abstract

The problem of drug interactions is becoming more and more important in clinical practice. When using immunosuppressive drugs, the risk of pharmacoki­netic interactions increases, which is directly related to their pharmacokinetic-pharmacodynamic profile. Knowledge of the most common interactions that occur in clinical practice allows for their active pre­vention, which in turn increases both the effective­ness and safety of the treatment used.