Vol 2, No 3 (2009)
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Published online: 2009-10-29

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Problemy terapeutyczne w leczeniu chorych z błoniastym kłębuszkowym zapaleniem nerek

Sławomir Lizakowski, Bolesław Rutkowski
Forum Nefrologiczne 2009;2(3):141-149.

Abstract

Nefropatia błoniasta jest jedną z najczęstszych przyczyn zespołu nerczycowego u osób dorosłych. Przebieg choroby jest bardzo różnorodny - od łagodnego do szybkiej progresji w kierunku niewydolności nerek. Obecnie trwają poszukiwania najlepszego algorytmu terapeutycznego dla tej postaci kłębuszkowego zapalenia nerek. Do tej pory ustaloną pozycję w leczeniu immunosupresyjnym ma połączenie glikokortykoidów i chlorambucilu lub cyklofosfamidu. Poszukiwane są schematy leczenia równie skuteczne, lecz obarczone mniejszą liczbą działań niepożądanych.

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